Madhusudhan Savitha, Keane Pearse A, Denniston Alastair K
Centre for Rare Diseases, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
J Ophthalmic Inflamm Infect. 2016 Dec;6(1):9. doi: 10.1186/s12348-016-0073-4. Epub 2016 Mar 10.
A challenge in the management of 'white dot syndromes' is the lack of sensitive objective measures of disease activity. Retinal thickness maps from spectral domain optical coherence tomography (SD-OCT) inform treatment decisions in other retinal conditions such as age-related macular degeneration and diabetic maculopathy. In this report, we demonstrate their value in providing quantitative monitoring of a patient with punctate inner choroidopathy (PIC). Retinal thickness maps referenced against a baseline scan reliably detected focal areas of increased macular volume in active PIC lesions during symptomatic episodes, highlighting these as 'hot spots' that could be quantified, providing an objective basis for treatment decisions.
“白点综合征”管理中的一个挑战是缺乏对疾病活动的敏感客观测量方法。光谱域光学相干断层扫描（SD-OCT）生成的视网膜厚度图可为年龄相关性黄斑变性和糖尿病性黄斑病变等其他视网膜疾病的治疗决策提供依据。在本报告中，我们展示了这些图在定量监测点状内层脉络膜病变（PIC）患者方面的价值。与基线扫描相对照的视网膜厚度图在症状发作期间能可靠地检测到活动性PIC病变中黄斑体积增加的局灶性区域，将这些区域突出显示为可量化的“热点”，为治疗决策提供了客观依据。
