Department of Gastroenterology and Hepatology, Niigata City General Hospital, Niigata, Japan.
United European Gastroenterol J. 2016 Feb;4(1):62-9. doi: 10.1177/2050640615581966. Epub 2015 Apr 9.
We previously reported the techniques and usefulness of simultaneous combined balloon-occluded retrograde transvenous obliteration (B-RTO) and partial splenic embolization (PSE), based on the hypothesis that concomitant PSE can diminish the increase in portal venous pressure after B-RTO.
After experiencing more cases and performing longer-term follow-up, we re-evaluated the efficacy of simultaneous combined B-RTO and PSE for gastric fundal varices (GVs).
We performed B-RTO in 36 consecutive patients treated for GVs from 2005 to 2013. Twenty-three patients underwent simultaneous combined B-RTO and PSE (Group 1) and 13 underwent B-RTO monotherapy (Group 2). The outcomes were retrospectively evaluated.
There were no significant differences in baseline characteristics between the two groups except that the splenic volumes were larger in Group 1 than 2. B-RTO was technically successful in 21 of 23 patients (91.3%) in Group 1 and in 12 of 13 patients (92.3%) in Group 2. In all patients with ruptured GVs (six in Group 1 and five in Group 2), complete hemostasis was obtained by B-RTO. Exacerbation of esophageal varices was significantly less frequent in Group 1 than 2 (p = 0.0017).
Concomitant PSE with B-RTO may contribute to prevention of the exacerbation of esophageal varices after B-RTO.
我们之前报告了同时进行球囊阻塞逆行经静脉闭塞(B-RTO)和部分脾栓塞术(PSE)的技术和实用性,基于同时进行 PSE 可以减少 B-RTO 后门静脉压力增加的假设。
在经历了更多病例并进行了更长时间的随访后,我们重新评估了同时进行 B-RTO 和 PSE 治疗胃底静脉曲张(GVs)的疗效。
我们对 2005 年至 2013 年间接受 GVs 治疗的 36 例连续患者进行了 B-RTO。23 例患者同时进行了 B-RTO 和 PSE(第 1 组),13 例患者仅进行了 B-RTO 治疗(第 2 组)。回顾性评估了结果。
两组患者的基线特征除脾脏体积第 1 组大于第 2 组外,无明显差异。第 1 组 23 例患者中有 21 例(91.3%)和第 2 组 13 例患者中有 12 例(92.3%)的 B-RTO 技术成功。在所有破裂的 GVs 患者中(第 1 组 6 例,第 2 组 5 例),B-RTO 均获得了完全止血。第 1 组食管静脉曲张加重的发生率明显低于第 2 组(p = 0.0017)。
B-RTO 同时进行 PSE 可能有助于预防 B-RTO 后食管静脉曲张的加重。