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有氧运动和抗阻运动可改变冠心病的危险因素。

Aerobic and resistive exercise modify risk factors for coronary heart disease.

作者信息

Goldberg A P

机构信息

Division of Geriatrics, Johns Hopkins School of Medicine, Francis Scott Key Medical Center, Baltimore, MD 21224.

出版信息

Med Sci Sports Exerc. 1989 Dec;21(6):669-74. doi: 10.1249/00005768-198912000-00008.

Abstract

An awareness of the health-related benefits of regular physical activity, prudent diet, and cessation of cigarette smoking are some of the mechanisms by which risk factors for coronary heart disease (CHD) and the incidence of complications of atherosclerosis have declined in the American population. Exercise training is associated with improvements in lipid and glucose metabolism that are manifested by enhanced insulin sensitivity, improved glucose tolerance, increased high density lipoprotein cholesterol levels, reduced triglyceride and low density lipoprotein cholesterol levels, and reductions in blood pressure. In addition to reduced risk factors for atherosclerosis, physically conditioned individuals have better cardiovascular function at rest and during exercise than their inactive peers. Thus, exercising training reduces morbidity and mortality from atherosclerotic complications through both direct (cardiovascular) and indirect (risk factor modification) mechanisms. Many studies demonstrate a strong association between regular physical activity and reduced risk for CHD. This article provides a review of risk factors for CHD and the potential health benefits of aerobic and resistive exercise. The time seems apt for the institution of multifactorial cardiovascular risk prevention programs in which aerobic and resistive exercise are combined with prudent diet therapy and smoking cessation to reduce risk factors for CHD.

摘要

认识到定期进行体育锻炼、合理饮食和戒烟对健康有益,是美国人群中心脏病(CHD)风险因素及动脉粥样硬化并发症发病率下降的部分原因。运动训练与脂质和葡萄糖代谢的改善相关,表现为胰岛素敏感性增强、葡萄糖耐量改善、高密度脂蛋白胆固醇水平升高、甘油三酯和低密度脂蛋白胆固醇水平降低以及血压下降。除了降低动脉粥样硬化的风险因素外,身体素质良好的个体在休息和运动时的心血管功能比不运动的同龄人更好。因此,运动训练通过直接(心血管)和间接(风险因素改变)机制降低动脉粥样硬化并发症的发病率和死亡率。许多研究表明,定期进行体育锻炼与降低冠心病风险之间存在密切关联。本文综述了冠心病的风险因素以及有氧和抗阻运动对健康的潜在益处。现在似乎适合开展多因素心血管疾病风险预防项目,将有氧和抗阻运动与合理饮食疗法及戒烟相结合,以降低冠心病的风险因素。

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