Jouret G, Bounemeur R, Presle A, Takin R
Service de dermatologie, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France.
Service d'accueil des urgences, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France.
Ann Dermatol Venereol. 2016 Apr;143(4):275-8. doi: 10.1016/j.annder.2016.01.006. Epub 2016 Mar 8.
Crusted scabies, also known as Norwegian scabies, is a rare and extremely debilitating form of Sarcoptes scabiei var. hominis infestation that generally occurs in immunosuppressed patients. Herein, we report a "historic" and fatal case.
A 52-year-old woman was admitted to the emergency department presenting crusted dermatitis together with extreme deterioration of her general condition. Her general practitioner had initiated dermo-corticosteroid therapy for suspected atopic dermatitis two months earlier, and she had been confined to bed for the previous 10 days. Her son presented pruritus that became worse at night. On examination the patient was moaning, dehydrated and confused and her entire skin was hyperkeratotic, with very thick, yellowish, cracked crusts covering 40 % of her body. Tests indicated severe water and electrolytic disorders as well as Staphylococcus aureus bacteremia. A tape test established the diagnosis of crusted scabies. The severity was grade III on the Davis clinical grading scale. The patient showed signs of multi-organ failure and was transferred to intensive care, but she died during the night.
This case is remarkable for its historic severity. In France, scabies infestation is a re-emerging disease and has been a public health priority since 2012. The rare hyperkeratotic form is not fully understood and frequently diagnosed late, in some cases with a fatal outcome.
结痂性疥疮,又称挪威疥疮,是一种罕见且极为衰弱的人型疥螨感染形式,通常发生在免疫抑制患者中。在此,我们报告一例“历史性”致命病例。
一名52岁女性因结痂性皮炎及全身状况极度恶化被收入急诊科。两个月前,她的全科医生因怀疑特应性皮炎开始给予皮肤糖皮质激素治疗,此前她已卧床10天。她的儿子出现夜间加重的瘙痒。检查时,患者呻吟、脱水且意识模糊,全身皮肤角化过度,有非常厚的黄色结痂,覆盖身体40%。检查显示严重的水电解质紊乱以及金黄色葡萄球菌菌血症。胶带试验确诊为结痂性疥疮。根据戴维斯临床分级量表,严重程度为III级。患者出现多器官功能衰竭迹象,被转入重症监护室,但于夜间死亡。
该病例因其历史性严重程度而引人注目。在法国,疥疮感染是一种再度出现的疾病,自2012年以来一直是公共卫生重点。这种罕见的角化过度形式尚未完全了解,且常常诊断较晚,在某些情况下会导致致命后果。