Morris M J, Newland R C, Pheils M T, Macpherson J G
Aust N Z J Surg. 1977 Jun;47(3):365-8. doi: 10.1111/j.1445-2197.1977.tb04304.x.
Out of 338 patients undergoing laparotomy and resection of a primary colorectal carcinoma, 49 (14-5%) were folnd to have liver metastases. The average age was 70 years. The median period of survival was 11-4 months. The histological grade of malignancy of the primary tumour did not appear to influence the survival rate. Compared with similar tumours in patients without hepatic metastases, the primary growth showed a significantly increased incidence of venous invasion, a higher grade of malignancy, and a more frequent origin from the right colon. When the local spread of the primary tumours was investigated it was found that one-third of them had not progressed beyond Stage Dukes A or B.
在338例行剖腹手术并切除原发性结直肠癌的患者中，发现49例（14.5%）有肝转移。平均年龄为70岁。中位生存期为11.4个月。原发性肿瘤的组织学恶性程度似乎不影响生存率。与无肝转移患者的类似肿瘤相比，原发性肿瘤的静脉侵犯发生率显著增加，恶性程度更高，且更常起源于右半结肠。当对原发性肿瘤的局部扩散情况进行研究时，发现其中三分之一的肿瘤尚未进展到杜克A期或B期以外。
