Amutha Anandakumar, Mohan Viswanathan
Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-communicable Diseases Prevention and Control, Gopalapuram, Chennai, India.
Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-communicable Diseases Prevention and Control, Gopalapuram, Chennai, India.
J Diabetes Complications. 2016 Jul;30(5):951-7. doi: 10.1016/j.jdiacomp.2016.02.009. Epub 2016 Feb 9.
Diabetes mellitus is one of the most common endocrine disorders in children. Earlier, diabetes in children was almost exclusively type 1 diabetes. Recently, the scenario has changed and increasing numbers of children and adolescent T2DM are being diagnosed. As the epidemic of T2DM shifts to children and adolescents, there is an increased risk of development of micro and macrovascular complications. This could potentially affect the economy of the nation apart from posing a large burden to the individual and his or her family. Prevention and treatment are especially important, given the fact that onset at an early age increases the risk of developing micro and macrovascular complications due to increased duration of exposure to hyperglycemia and other metabolic abnormalities. Diagnosing children and adolescents with T2DM early and instituting good control of all risk factors could yield good results in the prevention of long term complications of diabetes. This review focuses on the prevalence of complications of diabetes among children and adolescents with T2DM.
糖尿病是儿童中最常见的内分泌疾病之一。以前，儿童糖尿病几乎全是1型糖尿病。近来，情况有所变化，越来越多的儿童和青少年被诊断为2型糖尿病。随着2型糖尿病的流行转向儿童和青少年，微血管和大血管并发症的发生风险增加。这除了给个人及其家庭带来巨大负担外，还可能影响国家经济。鉴于早年发病会因高血糖和其他代谢异常暴露时间延长而增加发生微血管和大血管并发症的风险，预防和治疗尤为重要。早期诊断儿童和青少年2型糖尿病并对所有风险因素进行良好控制，在预防糖尿病长期并发症方面可能会取得良好效果。本综述重点关注2型糖尿病儿童和青少年中糖尿病并发症的患病率。
