Mahta Ali, Katz Paul M, Kamel Hooman, Azizi S Ausim
Department of Neurology, Temple University School of Medicine, Philadelphia, PA, USA; Department of Neurology, Columbia University Medical Center, 177 Ft. Washington Avenue, 8th floor, MHB 8GS, New York, NY 10032, USA; Department of Neurology, Weill Cornell Medical College, New York, NY, USA.
Department of Neurology, Temple University School of Medicine, Philadelphia, PA, USA.
J Clin Neurosci. 2016 Aug;30:56-59. doi: 10.1016/j.jocn.2015.11.028. Epub 2016 Mar 10.
This paper aimed to test the hypothesis that intraventricular extension of spontaneous intracerebral hemorrhage (ICH) in the absence of hydrocephalus is not associated with increased mortality or severe disability. We performed a retrospective consecutive cohort study of patients with primary spontaneous ICH who were admitted to a single institution. Multivariate logistic regression analysis was used to assess the association of each variable with functional outcome as measured by the modified Rankin Scale (mRS). A total of 164 patients met our inclusion criteria and were included in the study. Only hydrocephalus (p=0.002) and hematoma volume (p=0.006) were significantly associated with mortality or poor functional outcome (mRS of 3 to 6). In contrast, the presence of intraventricular hematoma was not independently associated with poor functional outcome. The presence of intraventricular extension of ICH in the absence of hydrocephalus may not increase mortality or disability.
在无脑积水的情况下，自发性脑出血（ICH）的脑室内扩展与死亡率增加或严重残疾无关。我们对入住单一机构的原发性自发性ICH患者进行了一项回顾性连续队列研究。采用多变量逻辑回归分析来评估每个变量与改良Rankin量表（mRS）所衡量的功能结局之间的关联。共有164例患者符合我们的纳入标准并被纳入研究。仅脑积水（p = 0.002）和血肿体积（p = 0.006）与死亡率或功能结局不佳（mRS为3至6）显著相关。相比之下，脑室内血肿的存在与功能结局不佳并无独立关联。在无脑积水的情况下，ICH脑室内扩展的存在可能不会增加死亡率或残疾率。
