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Amylo-1,6-glucosidase/4-alpha-glucanotransferase: use of reversible substrate model inhibitors to study the binding and active sites of rabbit muscle debranching enzyme.

作者信息

Gillard B K, Nelson T E

出版信息

Biochemistry. 1977 Sep 6;16(18):3978-87. doi: 10.1021/bi00637a007.

DOI:10.1021/bi00637a007
PMID:269742
Abstract
摘要

相似文献

1
Amylo-1,6-glucosidase/4-alpha-glucanotransferase: use of reversible substrate model inhibitors to study the binding and active sites of rabbit muscle debranching enzyme.淀粉-1,6-葡萄糖苷酶/4-α-葡聚糖转移酶：利用可逆底物模型抑制剂研究兔肌肉脱支酶的结合位点和活性位点
Biochemistry. 1977 Sep 6;16(18):3978-87. doi: 10.1021/bi00637a007.
2
Amylo-1,6-glucosidase/4-alpha-glucanotransferase. Reaction of rabbit muscle debranching enzyme with an active site-directed irreversible inhibitor, 1-S-dimethylarsino-1-thio-beta-D-glucopyranoside.淀粉-1,6-葡萄糖苷酶/4-α-葡聚糖转移酶。兔肌肉脱支酶与活性位点导向不可逆抑制剂1-S-二甲基胂基-1-硫代-β-D-吡喃葡萄糖苷的反应。
J Biol Chem. 1980 Sep 25;255(18):8451-7.
3
Structure of the polysaccharide formed by incubating glycogen with D-[14C]glucose in the presence of the glycogen debranching enzyme [amylo-(1 linked to 6)-glucosidase-4-alpha-glucanotransferase].在糖原脱支酶[淀粉-(1,6)-葡糖苷酶-4-α-葡聚糖转移酶]存在的情况下，将糖原与D-[¹⁴C]葡萄糖一起孵育形成的多糖的结构。
Carbohydr Res. 1978 Mar;61:265-77. doi: 10.1016/s0008-6215(00)84487-0.
4
Discrimination of porcine glycogen debranching enzyme isozymes by the ratios of their 4-alpha-glucanotransferase and amylo-alpha-1,6-glucosidase activities.通过 4-α-葡聚糖转移酶和淀粉α-1,6-葡萄糖苷酶活性的比值来区分猪糖原脱支酶同工酶。
J Biochem. 2010 Jun;147(6):851-6. doi: 10.1093/jb/mvq019. Epub 2010 Feb 17.
5
Donor substrate specificity of 4-alpha-glucanotransferase of porcine liver glycogen debranching enzyme and complementary action to glycogen phosphorylase on debranching.猪肝糖原脱支酶4-α-葡聚糖转移酶的供体底物特异性及其在脱支过程中对糖原磷酸化酶的互补作用。
J Biochem. 2008 Mar;143(3):435-40. doi: 10.1093/jb/mvm240. Epub 2008 Jan 2.
6
[Cyclodextrin glucanotransferase from Klebsiella pneumoniae. 2. Significance of the enzyme for the metabolism of cyclodextrins by Klebsiella pneumoniae M 5 al (author's transl)].[肺炎克雷伯菌的环糊精葡糖基转移酶。2. 该酶对肺炎克雷伯菌M5al代谢环糊精的意义（作者译）]
Arch Microbiol. 1977 May 13;113(1-2):49-56. doi: 10.1007/BF00428579.
7
Inspection of the activator binding site for 4-alpha-glucanotransferase in porcine liver glycogen debranching enzyme with fluorogenic dextrins.用荧光糊精检测猪肝糖原脱支酶中4-α-葡聚糖转移酶的激活剂结合位点。
J Biochem. 2009 May;145(5):585-90. doi: 10.1093/jb/mvp012. Epub 2009 Jan 20.
8
Essential dextrin structure as donor substrate for 4-α-glucanotransferase in glycogen debranching enzyme.糖原脱支酶中 4-α-葡聚糖转移酶的必需糊精结构作为供体底物。
J Biochem. 2024 Jul 31;176(2):109-117. doi: 10.1093/jb/mvae030.
9
Reassessment of the catalytic mechanism of glycogen debranching enzyme.糖原脱支酶催化机制的重新评估
Biochemistry. 1991 Feb 5;30(5):1419-24. doi: 10.1021/bi00219a036.
10
Active site mapping of amylo-alpha-1,6-glucosidase in porcine liver glycogen debranching enzyme using fluorogenic 6-O-alpha-glucosyl-maltooligosaccharides.使用荧光6-O-α-葡糖基麦芽寡糖对猪肝糖原脱支酶中的淀粉α-1,6-葡萄糖苷酶进行活性位点定位。
J Biochem. 2007 May;141(5):627-34. doi: 10.1093/jb/mvm065. Epub 2007 Feb 21.

引用本文的文献

1
Molecular architecture and catalytic mechanism of human glycogen debranching enzyme.人类糖原脱支酶的分子结构与催化机制
Nat Commun. 2025 Jul 1;16(1):5962. doi: 10.1038/s41467-025-61077-6.
2
Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations.糖原脱支酶的晶体结构及其催化作用和致病突变的见解
Nat Commun. 2016 Apr 18;7:11229. doi: 10.1038/ncomms11229.
3
Distinct mutations in the glycogen debranching enzyme found in glycogen storage disease type III lead to impairment in diverse cellular functions.
糖原贮积病III型中发现的糖原脱支酶的不同突变会导致多种细胞功能受损。
Hum Mol Genet. 2009 Jun 1;18(11):2045-52. doi: 10.1093/hmg/ddp128. Epub 2009 Mar 19.
4
Cyclization reaction catalyzed by glycogen debranching enzyme (EC 2.4.1.25/EC 3.2.1.33) and its potential for cycloamylose production.糖原脱支酶（EC 2.4.1.25/EC 3.2.1.33）催化的环化反应及其生产环糊精的潜力。
Appl Environ Microbiol. 2002 Sep;68(9):4233-9. doi: 10.1128/AEM.68.9.4233-4239.2002.
5
Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease.糖原脱支酶：III型糖原贮积病的纯化、抗体特性鉴定及免疫印迹分析
Am J Hum Genet. 1987 Dec;41(6):1002-15.
6
GLC3 and GHA1 of Saccharomyces cerevisiae are allelic and encode the glycogen branching enzyme.酿酒酵母的GLC3和GHA1是等位基因，编码糖原分支酶。
Mol Cell Biol. 1992 Jan;12(1):22-9. doi: 10.1128/mcb.12.1.22-29.1992.