癌胚抗原：在人类结直肠癌转移中的作用
Carcinoembryonic antigen: function in metastasis by human colorectal carcinoma.
作者信息
Jessup J M, Thomas P
机构信息
Department of Surgery, University of Texas M.D. Anderson Cancer Center, Houston.
出版信息
Cancer Metastasis Rev. 1989 Dec;8(3):263-80. doi: 10.1007/BF00047341.
PMID:2697474
Abstract
Carcinoembryonic antigen (CEA) is a glycoprotein that has been useful as a tumor marker to predict recurrence in gastrointestinal malignancies, but whose biological function has not been elucidated. With the recent evidence that CEA is a member of the immunoglobulin supergene family, CEA may be involved in intercellular recognition and binding. This review examines the role that CEA plays in the development of metastases by colorectal carcinoma.
摘要
癌胚抗原（CEA）是一种糖蛋白，作为肿瘤标志物可用于预测胃肠道恶性肿瘤的复发，但其生物学功能尚未阐明。最近有证据表明CEA是免疫球蛋白超基因家族的成员，因此CEA可能参与细胞间的识别和结合。本文综述了CEA在结直肠癌转移发生过程中所起的作用。
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