Williams L R, Leggett R W
Health and Safety Research Division, Oak Ridge National Laboratory, Tennessee 37831-6383.
Clin Phys Physiol Meas. 1989 Aug;10(3):187-217. doi: 10.1088/0143-0815/10/3/001.
The lack of a reliable quantitative description of blood flow in man has hampered the development of accurate biokinetic models of essential elements, drugs, imaging agents, and carcinogens. In this paper we review and analyse data on blood flow and identify representative percentages of cardiac output and absolute blood flow rates to organs and tissues of man for use as reference values for biokinetic models. To keep the review and analysis to a manageable size we have limited attention to the resting state and have suggested reference values for absolute and relative flow rates only for adult males and females.
缺乏对人体血流的可靠定量描述阻碍了基本元素、药物、成像剂和致癌物精确生物动力学模型的发展。在本文中，我们回顾并分析了有关血流的数据，并确定了心输出量的代表性百分比以及人体各器官和组织的绝对血流速率，用作生物动力学模型的参考值。为了使回顾和分析保持在可管理的规模，我们将注意力限制在静息状态，并仅给出了成年男性和女性绝对和相对血流速率的参考值。
