The effect of shift work on gastrointestinal (GI) function: a review.

Recent statistics suggest approximately 20 percent of the American work force is engaged in shift work. The evidence which is reviewed in this manuscript suggests that shiftworkers are at risk for the development of gastrointestinal diseases or disorders. The susceptibility to shiftwork related gastrointestinal complaints may be related to the disruption of the individual's time structure. Central nervous system and endocrine mechanisms which may contribute to the pathogenesis of digestive diseases/disorders in shift workers are discussed.