Laboratoire de Psychologie des Pays de la Loire LPPL-EA 4638, Université de Nantes, France.
Centre Mémoire Ressources et Recherches, Centre Hospitalier Universitaire, Nantes, France.
J Gerontol B Psychol Sci Soc Sci. 2017 Oct 1;72(6):986-990. doi: 10.1093/geronb/gbw032.
This study explores the activation of the critical lure (CL) and its production in Deese-Roediger-McDermott (DRM) tasks in Alzheimer's disease and aging. In a previous lexical decision task including DRM lists, we showed that the activation of the CL occurs normally in Alzheimer's patients. Here, we reproduce this study and add a production (DRM) task in order to compare both processes in the same groups of participants.
Eighteen older adults and 20 Alzheimer's patients performed a conventional DRM task, followed by a lexical decision task with DRM lists intermixed with neutral words and nonwords.
Analyses indicated that Alzheimer's patients produced significantly fewer CLs than older participants in the DRM task, but that they showed, like older adults, shorter lexical decision latencies for CLs than for other types of words.
This study provides evidence that the low production of CLs regularly documented in Alzheimer's patients in the DRM paradigm is not necessarily explained by their nonactivation. The results are discussed in the light of the hypothesis of a rapid disappearance of the episodic mnemonic trace of the CLs in Alzheimer's patients.
本研究旨在探讨阿尔茨海默病和衰老患者中关键诱饵（CL）的激活及其在 Deese-Roediger-McDermott（DRM）任务中的产生。在之前包含 DRM 列表的词汇判断任务中，我们表明 CL 的激活在阿尔茨海默病患者中正常发生。在这里，我们复制了这项研究，并添加了一个产生（DRM）任务，以便在相同的参与者组中比较这两个过程。
18 名老年人和 20 名阿尔茨海默病患者完成了常规的 DRM 任务，随后进行了词汇判断任务，其中 DRM 列表与中性词和非词混合。
分析表明，与老年人相比，阿尔茨海默病患者在 DRM 任务中产生的 CL 明显较少，但他们的 CL 词汇判断潜伏期比其他类型的词更短。
本研究提供了证据表明，在 DRM 范式中，阿尔茨海默病患者经常记录到的 CL 产生较少的情况不一定是由于其未激活造成的。结果根据 CL 在阿尔茨海默病患者中快速消失的情景记忆痕迹的假设进行了讨论。
