HIV 感染患者机会性感染及其他合并感染的预防与治疗：2015 年 5 月
Prevention and treatment of opportunistic infections and other coinfections in HIV-infected patients: May 2015.
作者信息
Iribarren José Antonio, Rubio Rafael, Aguirrebengoa Koldo, Arribas Jose Ramón, Baraia-Etxaburu Josu, Gutiérrez Félix, Lopez Bernaldo de Quirós Juan Carlos, Losa Juan Emilio, Miró José Ma, Moreno Santiago, Pérez Molina José, Podzamczer Daniel, Pulido Federico, Riera Melchor, Rivero Antonio, Sanz Moreno José, Amador Concha, Antela Antonio, Arazo Piedad, Arrizabalaga Julio, Bachiller Pablo, Barros Carlos, Berenguer Juan, Caylá Joan, Domingo Pere, Estrada Vicente, Knobel Hernando, Locutura Jaime, López Aldeguer José, Llibre Josep Ma, Lozano Fernando, Mallolas Josep, Malmierca Eduardo, Miralles Celia, Miralles Pilar, Muñoz Agustín, Ocampo Agustín, Olalla Julián, Pérez Inés, Pérez Elías Ma Jesús, Pérez Arellano José Luis, Portilla Joaquín, Ribera Esteban, Rodríguez Francisco, Santín Miguel, Sanz Sanz Jesús, Téllez Ma Jesús, Torralba Miguel, Valencia Eulalia, Von Wichmann Miguel Angel
出版信息
Enferm Infecc Microbiol Clin. 2016 Oct;34(8):516.e1-516.e18. doi: 10.1016/j.eimc.2016.02.004. Epub 2016 Mar 11.
Despite the huge advance that antiretroviral therapy represents for the prognosis of infection by the human immunodeficiency virus (HIV), opportunistic infections (OIs) continue to be a cause of morbidity and mortality in HIV-infected patients. OIs often arise because of severe immunosuppression resulting from poor adherence to antiretroviral therapy, failure of antiretroviral therapy, or unawareness of HIV infection by patients whose first clinical manifestation of AIDS is an OI. The present article updates our previous guidelines on the prevention and treatment of various OIs in HIV-infected patients, namely, infections by parasites, fungi, viruses, mycobacteria, and bacteria, as well as imported infections. The article also addresses immune reconstitution inflammatory syndrome.
尽管抗逆转录病毒疗法在改善人类免疫缺陷病毒（HIV）感染预后方面取得了巨大进展，但机会性感染（OI）仍是HIV感染患者发病和死亡的原因。OI的发生通常是由于抗逆转录病毒治疗依从性差、抗逆转录病毒治疗失败导致的严重免疫抑制，或者是首次临床表现为OI的艾滋病患者未意识到自己感染了HIV。本文更新了我们之前关于HIV感染患者各种OI预防和治疗的指南，即寄生虫、真菌、病毒、分枝杆菌和细菌感染以及输入性感染。本文还讨论了免疫重建炎症综合征。
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