Champ Colin E, Francis Lanie, Klement Rainer J, Dickerman Roger, Smith Ryan P
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15215, USA; Department of Integrative Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA.
Department of Integrative Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA; Department of Medical Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA.
Prostate Cancer. 2016;2016:9462975. doi: 10.1155/2016/9462975. Epub 2016 Feb 10.
Over the past decade, significant data have shown that obese men experience a survival detriment after treatment for prostate cancer. While methods to combat obesity are of utmost importance for the prostate cancer patient, newer data reveal the overall metabolic improvements that accompany increased activity levels and intense exercise beyond weight loss. Along these lines, a plethora of data have shown improvement in prostate cancer-specific outcomes after treatment accompanied with these activity levels. This review discusses the metabolic mechanisms in which increased activity levels and exercise can help improve both outcomes for men treated for prostate cancer while lowering the side effects of treatment.
在过去十年中,大量数据表明肥胖男性在接受前列腺癌治疗后生存受到不利影响。虽然对抗肥胖的方法对前列腺癌患者至关重要,但新数据显示,除了体重减轻外,活动水平增加和高强度运动还会带来整体代谢改善。据此,大量数据表明,在达到这些活动水平后,前列腺癌治疗后的特定结果有所改善。本综述讨论了活动水平增加和运动有助于改善前列腺癌男性患者的治疗结果并降低治疗副作用的代谢机制。