Haricharan Svasti, Lei Jonathan, Ellis Matthew
Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Cancer Cell. 2016 Mar 14;29(3):249-250. doi: 10.1016/j.ccell.2016.02.017.
In this issue of Cancer Cell, Sflomos et al. (2016) describe a robust preclinical animal model of ER⁺ breast cancer. The authors identify the critical role of the breast microenvironment in determining hormone response of ER⁺ breast cancer cells and in driving the luminal phenotype of breast cancer.
在本期《癌细胞》杂志中，斯弗洛莫斯等人（2016年）描述了一种强大的雌激素受体阳性（ER⁺）乳腺癌临床前动物模型。作者们确定了乳腺微环境在决定ER⁺乳腺癌细胞的激素反应以及推动乳腺癌管腔表型方面的关键作用。
