Fernandez-Hernandez Jesus M, Longhi Elena, Cysewski Robert, Polo Federico, Josel Hans-Peter, De Cola Luisa
Westfälische Wilhelms-Universität , Center for Nanotechnology (CeNTech), Heisenbergstrasse 11, 48149 Münster, Germany.
Roche Diagnostics GmbH , Nonnenwald 2, 82372 Penzberg, Germany.
Anal Chem. 2016 Apr 19;88(8):4174-8. doi: 10.1021/acs.analchem.6b00312. Epub 2016 Mar 28.
A family of neutral bis-cyclometalated iridium complexes [Ir(C^N)2(LX)] has been investigated as ECL labels under immunoassay conditions. Among them, the complex based on phenylphenanthridine (pphent) as the C^N ligand, exhibits outstanding performance and it is a candidate to substitute the commercially available Ru-based label in diagnostics.
一类中性双环金属化铱配合物[Ir(C^N)2(LX)]已在免疫分析条件下作为电化学发光（ECL）标记物进行了研究。其中，以苯基菲啶（pphent）作为C^N配体的配合物表现出优异的性能，是诊断领域中替代市售钌基标记物的候选物。
