使用磁聚焦增强型侧向流动传感器对微生物细胞进行超灵敏检测。
Ultrasensitive detection of microbial cells using magnetic focus enhanced lateral flow sensors.
作者信息
Ren Wen, Cho Il-Hoon, Zhou Zhongwu, Irudayaraj Joseph
机构信息
Department of Agricultural and Biological Engineering, Bindley Bioscience Center, Purdue Center for Cancer research, Purdue University, West Lafayette, Indiana 47907, USA.
出版信息
Chem Commun (Camb). 2016 Apr 7;52(27):4930-3. doi: 10.1039/c5cc10240e. Epub 2016 Mar 15.
PMID:26978736
Abstract
We report on an improved lateral flow immunoassay (LFIA) sensor with a magnetic focus for ultrasensitive naked-eye detection of pathogenic microorganisms at a near single cell limit without any pre-enrichment steps, by allowing the magnetic probes to focus the labelled pathogens to the target zone of the LF strip.
摘要
我们报道了一种改进的侧向流动免疫分析（LFIA）传感器，该传感器具有磁聚焦功能，通过使磁性探针将标记的病原体聚焦到LF试纸条的目标区域，能够在无需任何预富集步骤的情况下，以接近单细胞的极限对致病微生物进行超灵敏的裸眼检测。
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