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纳米材料在用于检测传染病的生物传感器中的应用。

Nanomaterial application in bio/sensors for the detection of infectious diseases.

作者信息

Sheikhzadeh Elham, Beni Valerio, Zourob Mohammed

机构信息

Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.

Digital Systems, Department Smart Hardware, Unit Bio-& Organic Electronics, RISE Acreo, Research Institutes of Sweden, Norrkoping, 60221, Sweden.

出版信息

Talanta. 2021 Aug 1;230:122026. doi: 10.1016/j.talanta.2020.122026. Epub 2020 Dec 17.

Abstract

Infectious diseases are a potential risk for public health and the global economy. Fast and accurate detection of the pathogens that cause these infections is important to avoid the transmission of the diseases. Conventional methods for the detection of these microorganisms are time-consuming, costly, and not applicable for on-site monitoring. Biosensors can provide a fast, reliable, and point of care diagnostic. Nanomaterials, due to their outstanding electrical, chemical, and optical features, have become key players in the area of biosensors. This review will cover different nanomaterials that employed in electrochemical, optical, and instrumental biosensors for infectious disease diagnosis and how these contributed to enhancing the sensitivity and rapidity of the various sensing platforms. Examples of nanomaterial synthesis methods as well as a comprehensive description of their properties are explained. Moreover, when available, comparative data, in the presence and absence of the nanomaterials, have been reported to further highlight how the usage of nanomaterials enhances the performances of the sensor.

摘要

传染病对公共卫生和全球经济构成潜在风险。快速准确地检测引起这些感染的病原体对于避免疾病传播至关重要。检测这些微生物的传统方法耗时、成本高且不适用于现场监测。生物传感器可以提供快速、可靠的即时诊断。纳米材料因其出色的电学、化学和光学特性,已成为生物传感器领域的关键要素。本综述将涵盖用于传染病诊断的电化学、光学和仪器化生物传感器中使用的不同纳米材料,以及这些材料如何有助于提高各种传感平台的灵敏度和快速性。文中解释了纳米材料合成方法的示例及其特性的全面描述。此外,在有可用数据的情况下,还报告了存在和不存在纳米材料时的对比数据,以进一步突出纳米材料的使用如何提高传感器的性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7bb/7854185/d8ccce9cee82/ga1_lrg.jpg

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