Nicholls Stuart G, Langan Sinéad M, Benchimol Eric I, Moher David
Children's Hospital of Eastern Ontario (CHEO) Research Institute, c/o RI Administration Offices, Research Building 1, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
BMC Med. 2016 Mar 16;14:44. doi: 10.1186/s12916-016-0587-5.
Improving the transparency and quality of reporting in biomedical research is considered ethically important; yet, this is often based on practical reasons such as the facilitation of peer review. Surprisingly, there has been little explicit discussion regarding the ethical obligations that underpin reporting guidelines. In this commentary, we suggest a number of ethical drivers for the improved reporting of research. These ethical drivers relate to researcher integrity as well as to the benefits derived from improved reporting such as the fair use of resources, minimizing risk of harms, and maximizing benefits. Despite their undoubted benefit to reporting completeness, questions remain regarding the extent to which reporting guidelines can influence processes beyond publication, including researcher integrity or the uptake of scientific research findings into policy or practice. Thus, we consider investigation on the effects of reporting guidelines an important step in providing evidence of their benefits.
提高生物医学研究报告的透明度和质量在伦理上被认为是重要的；然而，这往往基于诸如便于同行评审等实际原因。令人惊讶的是，对于支撑报告指南的伦理义务，几乎没有明确的讨论。在这篇评论中，我们提出了一些促进改进研究报告的伦理驱动因素。这些伦理驱动因素涉及研究人员的诚信，以及改进报告所带来的益处，如资源的合理使用、将危害风险降至最低和利益最大化。尽管报告指南对报告完整性有无疑的益处，但对于报告指南能够在多大程度上影响出版之外的过程，包括研究人员的诚信或科研成果在政策或实践中的应用，仍存在疑问。因此，我们认为对报告指南的效果进行调查是提供其益处证据的重要一步。
