Pallavee P, Samal Rupal, Begum Jasmina, Ghose Seetesh
a Department of Obstetrics and Gynaecology , Mahatma Gandhi Medical College and Research Institute , Pillaiyarkuppam , Pondy, Cuddalore Main Road , Puducherry , India.
J Obstet Gynaecol. 2016 Aug;36(6):760-761. doi: 10.3109/01443615.2016.1157152. Epub 2016 Mar 16.
Misoprostol is a well known abortifacient. It can cause teratogenicity like Mobius sequence and terminal transverse limb defects. We report a rare case of proximal focal femoral deficiency with fibular hemimelia in a woman who had attempted abortion with self-administered misoprostol and later continued the pregnancy. Though the absolute risk of congenital malformations with its use is low ∼1%, this should be clearly communicated to the women requesting abortion to help them make fully informed reproductive health decisions.
米索前列醇是一种众所周知的堕胎药。它可导致如默比厄斯序列和末端横断肢体缺陷等致畸性。我们报告了一例罕见病例，一名女性自行服用米索前列醇试图堕胎，之后继续妊娠，结果出现近端局灶性股骨发育不全并伴有腓骨半侧发育不全。尽管使用该药导致先天性畸形的绝对风险较低，约为1%，但应将这一情况明确告知要求堕胎的女性，以帮助她们做出充分知情的生殖健康决策。
