Department of Medicine, University British Columbia, Vancouver, British Columbia, Canada.
Providence Health Care Research Institute, Vancouver, British Columbia, Canada.
Thorax. 2016 Jul;71(7):664-6. doi: 10.1136/thoraxjnl-2015-207994. Epub 2016 Mar 15.
We sought to determine whether patients with obstructive sleep apnoea (OSA) are at increased risk of occupational injury (OI). Patients referred to the University of British Columbia Hospital Sleep Laboratory for suspected OSA (May 2003 to July 2011 were recruited and rates and types of validated OI (that caused at least 1 day of disability) in the 5 years prior to polysomnography were calculated. In a sample of 1236, patients with OSA were twice as likely (OR=1.93, 95% CI 1.06 to 3.50, p=0.03) to suffer at least one OI compared with patients without OSA. This association was attenuated (OR=1.76, CI 0.86 to 3.59, p=0.12) after controlling for confounders. In a secondary analysis, patients with OSA were almost three times more likely (OR=2.88, CI 1.02 to 8.08, p=0.05) to suffer from an injury more likely related to reduced vigilance (eg, a fall or commercial motor vehicle crash) when compared with patients without OSA, and this again was attenuated after controlling for confounders (OR=2.42, CI 0.085 to 6.93, p=0.10).
我们试图确定阻塞性睡眠呼吸暂停（OSA）患者是否有更高的职业伤害（OI）风险。我们招募了 2003 年 5 月至 2011 年 7 月期间因疑似 OSA 而被转介到不列颠哥伦比亚大学医院睡眠实验室的患者，并计算了他们在进行多导睡眠图检查前 5 年内确诊的OI （导致至少 1 天残疾）的发生率和类型。在 1236 名患者中，有 OSA 的患者发生至少一次 OI 的可能性是没有 OSA 的患者的两倍（OR=1.93，95%CI 1.06 至 3.50，p=0.03）。在控制了混杂因素后，这种关联减弱（OR=1.76，CI 0.86 至 3.59，p=0.12）。在二次分析中，与没有 OSA 的患者相比，患有 OSA 的患者更有可能遭受与警觉性降低相关的伤害（例如跌倒或商业机动车事故）（OR=2.88，CI 1.02 至 8.08，p=0.05），这种关联在控制了混杂因素后再次减弱（OR=2.42，CI 0.085 至 6.93，p=0.10）。
