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Prospects for Moxidectin as a New Oral Treatment for Human Scabies.

作者信息

Mounsey Kate E, Bernigaud Charlotte, Chosidow Olivier, McCarthy James S

机构信息

Inflammation & Healing Research Cluster, School of Health and Sport Sciences, University of the Sunshine Coast, Maroochydore, Queensland, Australia.

Infectious Diseases & Immunology Division, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

出版信息

PLoS Negl Trop Dis. 2016 Mar 17;10(3):e0004389. doi: 10.1371/journal.pntd.0004389. eCollection 2016 Mar.

DOI:10.1371/journal.pntd.0004389
PMID:26985995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4795782/
Abstract
摘要

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本文引用的文献

1
Impact of an Ivermectin Mass Drug Administration on Scabies Prevalence in a Remote Australian Aboriginal Community.伊维菌素群体给药对澳大利亚偏远原住民社区疥疮患病率的影响。
PLoS Negl Trop Dis. 2015 Oct 30;9(10):e0004151. doi: 10.1371/journal.pntd.0004151. eCollection 2015 Oct.
2
Prevalence of scabies and impetigo worldwide: a systematic review.全球范围内疥疮和脓疱疮的患病率：系统评价。
Lancet Infect Dis. 2015 Aug;15(8):960-7. doi: 10.1016/S1473-3099(15)00132-2. Epub 2015 Jun 15.
3
Prospective study in a porcine model of sarcoptes scabiei indicates the association of Th2 and Th17 pathways with the clinical severity of scabies.一项针对疥螨的猪模型的前瞻性研究表明，Th2 和 Th17 途径与疥疮的临床严重程度相关。
PLoS Negl Trop Dis. 2015 Mar 2;9(3):e0003498. doi: 10.1371/journal.pntd.0003498. eCollection 2015 Mar.
4
Superiority of ivermectin 1% cream over metronidazole 0·75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial.伊维菌素 1%乳膏治疗酒渣鼻炎症性皮损优于甲硝唑 0.75%乳膏：一项随机、研究者盲法试验。
Br J Dermatol. 2015 Apr;172(4):1103-10. doi: 10.1111/bjd.13408. Epub 2015 Feb 11.
5
Scabies outbreaks in residential care homes: factors associated with late recognition, burden and impact. A mixed methods study in England.养老院疥疮暴发：与延迟识别、负担及影响相关的因素。英国的一项混合方法研究。
Epidemiol Infect. 2015 May;143(7):1542-51. doi: 10.1017/S0950268814002143. Epub 2014 Sep 8.
6
The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases.《2010年全球疾病负担研究：对被忽视热带病的解读与影响》
PLoS Negl Trop Dis. 2014 Jul 24;8(7):e2865. doi: 10.1371/journal.pntd.0002865. eCollection 2014 Jul.
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Treatment for crusted scabies: limitations and side effects of treatment with ivermectin.结痂性疥疮的治疗：伊维菌素治疗的局限性和副作用
J Nippon Med Sch. 2014;81(3):157-63. doi: 10.1272/jnms.81.157.
8
A randomized, single-ascending-dose, ivermectin-controlled, double-blind study of moxidectin in Onchocerca volvulus infection.一项随机、单剂量递增、伊维菌素对照、双盲的莫昔克丁治疗盘尾丝虫病的研究。
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Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway.疥疮螨无活性丝氨酸蛋白酶是人类补体凝集素途径的有效抑制剂。
PLoS Negl Trop Dis. 2014 May 22;8(5):e2872. doi: 10.1371/journal.pntd.0002872. eCollection 2014 May.
10
Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies.1%伊维菌素乳膏治疗丘疹脓疱型玫瑰痤疮的疗效和安全性：两项随机、双盲、赋形剂对照关键研究的结果
J Drugs Dermatol. 2014 Mar;13(3):316-23.