Jawad Huda, Bain Duncan S, Dawson Helen, Crawford Kate, Johnston Atholl, Tucker Arthur
Department of Clinical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom.
Department of Clinical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom.
J Vasc Surg Venous Lymphat Disord. 2014 Apr;2(2):160-5. doi: 10.1016/j.jvsv.2013.10.052. Epub 2014 Jan 28.
This study compares the effectiveness of a neuromuscular electrostimulation device (geko T-1; Firstkind Ltd, High Wycombe, UK) in enhancing lower limb blood perfusion with two leading intermittent pneumatic compression (IPC) devices, the Huntleigh Flowtron Universal (Huntleigh Healthcare Ltd, Cardiff, UK) and the Kendall SCD Express (Covidien plc, Dublin, Ireland). The subjects' tolerance of the devices was also compared.
Ten healthy subjects were recruited. The devices were fitted bilaterally, in a sequential manner, for 30 minutes. Ultrasound and laser Doppler fluxmetry assessments were performed.
The geko T-1 device was superior to both IPC devices in increasing both venous and arterial blood volume flow by ∼30% (95% confidence interval [CI], 23.7%-82.4%; P ≤ .001). The geko T-1 increased arterial blood velocity by 24% (95% CI, 9.7%-24.5%; P ≤ .001). A substantial increase in the total microcirculatory blood velocity by ∼370% (95% CI, 13.5%-39.7%) was reported after the use of the geko T-1 (P ≤ .001). With use of the visual analog scale, no significant differences in discomfort were found between the geko T-1 device and the IPC devices (P >.05).
The geko T-1 device is more effective than the IPC devices in increasing venous, arterial, and microcirculatory blood velocity. The devices studied were safe and well tolerated by healthy subjects.
本研究比较了一种神经肌肉电刺激设备（geko T-1；Firstkind有限公司，英国海威科姆）与两种领先的间歇性气动压迫（IPC）设备——Huntleigh Flowtron Universal（Huntleigh医疗保健有限公司，英国加的夫）和Kendall SCD Express（Covidien plc，爱尔兰都柏林）在增强下肢血液灌注方面的有效性。还比较了受试者对这些设备的耐受性。
招募了10名健康受试者。将这些设备双侧依次佩戴30分钟。进行了超声和激光多普勒血流仪评估。
geko T-1设备在增加静脉和动脉血容量流量方面比两种IPC设备都更有效，增加了约30%（95%置信区间[CI]，23.7%-82.4%；P≤0.001）。geko T-1使动脉血流速度提高了24%（95%CI，9.7%-24.5%；P≤0.001）。使用geko T-1后，据报告总微循环血流速度大幅增加了约370%（95%CI，13.5%-39.7%）（P≤0.001）。使用视觉模拟量表，未发现geko T-1设备与IPC设备在不适方面有显著差异（P>0.05）。
geko T-1设备在增加静脉、动脉和微循环血流速度方面比IPC设备更有效。所研究的设备对健康受试者是安全且耐受性良好的。
