Suppr超能文献

胰腺创伤的管理

Management of pancreatic trauma.

作者信息

Girard E, Abba J, Arvieux C, Trilling B, Sage P Y, Mougin N, Perou S, Lavagne P, Létoublon C

机构信息

Service de chirurgie digestive et de l'urgence, hôpital Michallon, CHU, boulevard de la Chantourne, 38700 La Tronche, France.

Réanimation post-chirurgicale, hôpital Michallon, CHU, boulevard de la Chantourne, 38700 La Tronche, France.

出版信息

J Visc Surg. 2016 Aug;153(4):259-68. doi: 10.1016/j.jviscsurg.2016.02.006. Epub 2016 Mar 16.

Abstract

INTRODUCTION

Pancreatic trauma (PT) is associated with high morbidity and mortality; the therapeutic options remain debated.

MATERIAL AND METHODS

Retrospective study of PT treated in the University Hospital of Grenoble over a 22-year span. The decision for initial laparotomy depended on hemodynamic status as well as on associated lesions. Main pancreatic duct lesions were always searched for. PT lesions were graded according to the AAST classification.

RESULTS

Of a total of 46 PT, 34 were grades II or I. Hemodynamic instability led to immediate laparotomy in 18 patients, for whom treatment was always drainage of the pancreatic bed; morbidity was 30%. Eight patients had grade III injuries, six of whom underwent immediate operation: three underwent splenopancreatectomy without any major complications while the other three who had simple drainage required re-operation for peritonitis, with one death related to pancreatic complications. Four patients had grades IV or V PT: two pancreatoduodenectomies were performed, with no major complication, while one patient underwent duodenal reconstruction with pancreatic drainage, complicated by pancreatic and duodenal fistula requiring a hospital stay of two months. The post-trauma course was complicated for all patients with main pancreatic duct involvement. Our outcomes were similar to those found in the literature.

CONCLUSION

In patients with distal PT and main pancreatic duct involvement, simple drainage is associated with high morbidity and mortality. For proximal PT, the therapeutic options of drainage versus pancreatoduodenectomy must be weighed; pancreatoduodenectomy may be unavoidable when the duodenum is injured as well. Two-stage (resection first, reconstruction later) could be an effective alternative in the emergency setting when there are other associated traumatic lesions.

摘要

引言

胰腺创伤(PT)与高发病率和死亡率相关;治疗方案仍存在争议。

材料与方法

对格勒诺布尔大学医院22年间治疗的PT进行回顾性研究。初始剖腹手术的决策取决于血流动力学状态以及相关损伤。始终要探查主胰管损伤情况。PT损伤根据美国创伤外科学会(AAST)分类进行分级。

结果

在总共46例PT中,34例为I级或II级。血流动力学不稳定导致18例患者立即接受剖腹手术,对这些患者的治疗始终是胰腺床引流;发病率为30%。8例患者为III级损伤,其中6例立即接受手术:3例行脾胰切除术,无任何重大并发症,而另外3例单纯引流的患者因腹膜炎需要再次手术,1例死于胰腺并发症。4例患者为IV级或V级PT:2例行胰十二指肠切除术,无重大并发症,而1例患者行十二指肠重建并胰腺引流,并发胰瘘和十二指肠瘘,住院两个月。所有主胰管受累的患者创伤后病程均复杂。我们的结果与文献报道相似。

结论

对于远端PT且主胰管受累的患者,单纯引流与高发病率和死亡率相关。对于近端PT,必须权衡引流与胰十二指肠切除术的治疗选择;当十二指肠也受伤时,胰十二指肠切除术可能不可避免。在存在其他相关创伤性损伤的紧急情况下,两阶段(先切除,后重建)可能是一种有效的替代方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验