Hax Jakob, Halvachizadeh Sascha, Jensen Kai Oliver, Berk Till, Teuber Henrik, Di Primio Teresa, Lefering Rolf, Pape Hans-Christoph, Sprengel Kai
Department of Trauma, University Hospital Zurich, 8091 Zurich, Switzerland.
Institute for Research in Operative Medicine (IFOM), Witten/Herdecke University, 51109 Cologne, Germany.
J Clin Med. 2021 Feb 11;10(4):700. doi: 10.3390/jcm10040700.
The pancreas is at risk of damage as a consequence of thoracolumbar spine injury. However, there are no studies providing prevalence data to support this assumption. Data from European hospitals documented in the TraumaRegister DGU (TR-DGU) between 2008-2017 were analyzed to estimate the prevalence of this correlation and to determine the impact on clinical outcome. A total of 44,279 patients with significant thoracolumbar trauma, defined on Abbreviated Injury Scale (AIS) as ≥2, were included. Patients transferred to another hospital within 48 h were excluded to prevent double counting. A total of 135,567 patients without thoracolumbar injuries (AIS ≤ 1) were used as control group. Four-hundred patients with thoracolumbar trauma had a pancreatic injury. Pancreatic injuries were more common after thoracolumbar trauma (0.90% versus (vs.) 0.51%, odds ratio (OR) 1.78; 95% confidence intervals (CI), 1.57-2.01). Patients with pancreatic injuries were more likely to be male (68%) and had a higher mean Injury Severity Score (ISS) than those without (35.7 ± 16.0 vs. 23.8 ± 12.4). Mean length of stay (LOS) in intensive care unit (ICU) and hospital was longer with pancreatic injury. In-hospital mortality was 17.5% with and 9.7% without pancreatic injury, respectively. Although uncommon, concurrent pancreatic injury in the setting of thoracolumbar trauma can portend a much more serious injury.
胸腰椎损伤可能会导致胰腺受损。然而,尚无研究提供患病率数据来支持这一假设。对2008年至2017年间创伤注册数据库DGU(TR-DGU)中记录的欧洲医院数据进行分析,以估计这种相关性的患病率,并确定其对临床结局的影响。总共纳入了44279例胸腰椎严重创伤患者,根据简明损伤定级标准(AIS)定义为≥2级。排除48小时内转至其他医院的患者以避免重复计数。总共135567例无胸腰椎损伤(AIS≤1)的患者作为对照组。400例胸腰椎创伤患者发生了胰腺损伤。胸腰椎创伤后胰腺损伤更为常见(0.90%对0.51%,比值比(OR)1.78;95%置信区间(CI),1.57 - 2.01)。胰腺损伤患者更可能为男性(68%),且其平均损伤严重程度评分(ISS)高于未发生胰腺损伤的患者(35.7±16.0对23.8±12.4)。胰腺损伤患者在重症监护病房(ICU)和医院的平均住院时间更长。住院死亡率在有胰腺损伤和无胰腺损伤的患者中分别为17.5%和9.7%。虽然不常见,但胸腰椎创伤合并胰腺损伤可能预示着更严重的损伤。