Faundez Tamara, Klee Philippe, Hanquinet Sylviane, Schwitzgebel Valérie, Burkhard Pierre R, Korff Christian M
Department of Pediatric Neurology, Child and Adolescent.
Endocrinology and Diabetes Unit, Department of Child and Adolescent.
Pediatrics. 2016 Apr;137(4). doi: 10.1542/peds.2014-3761. Epub 2016 Mar 24.
Diabetic striatopathy is a well-known complication of diabetes in adults. To our knowledge, only 2 cases have been reported in children. We here report the case of a teenager in whom diabetic striatopathy was revealed by the subacute appearance of hemichorea-hemiballism in the context of weight loss, polyuria, and polydipsia. Glycemia control allowed rapid clinical recovery despite established striatal lesions documented on MRI. We also discuss current hypotheses about pathophysiological processes underlying this entity.
糖尿病性纹状体病是成人糖尿病的一种常见并发症。据我们所知，儿童中仅报告过2例。我们在此报告一名青少年病例，该患者在体重减轻、多尿和烦渴的情况下，因偏侧舞蹈症-偏侧投掷症的亚急性发作而被诊断为糖尿病性纹状体病。尽管MRI显示有已形成的纹状体病变，但血糖控制使临床症状迅速恢复。我们还讨论了关于该疾病潜在病理生理过程的当前假说。
