Özgür Anıl, Esen Kaan, Kaleağası Hakan, Yılmaz Arda, Kara Engin
Department of Radiology, Faculty of Medicine, Mersin University, 34. Cadde, Çiftlikköy Kampüsü, 33343, Mersin, Turkey,
Emerg Radiol. 2015 Jun;22(3):347-9. doi: 10.1007/s10140-015-1308-7. Epub 2015 Mar 13.
Diabetic striatopathy is a rare and life-threatening manifestation of diabetes mellitus. The disease commonly affects individuals of Asian descent, females, and the elderly. Patients usually present with hemiballism-hemichorea caused by nonketotic hyperglycemia. Hemiballism-hemichorea is defined as involuntary continuous random appearing movement involving one side of the body. This movement disorder may develop secondary to stroke, diabetic striatopathy, neoplasm, infection, Wilson's disease, and thyrotoxicosis. Despite being rare, prompt recognition of a hyperglycemia-induced hemiballism-hemichorea is essential because the symptoms are reversible with correction of hyperglycemia. Diagnosis is possible based on blood analysis and neuroimaging findings. Laboratory tests reveal raised blood glucose and hemoglobin A1C levels which indicate poorly controlled diabetes. Neuroimaging provides suggestive findings of diabetic striatopathy which are hyperattenuation on computed tomography and hyperintensity on T1-weighted magnetic resonance imaging in the basal ganglia. In this case report, our aim is to present neuroimaging findings in an adult man with sudden onset of hemiballism associated with nonketotic hyperglycemia.
糖尿病性纹状体病是糖尿病一种罕见且危及生命的表现形式。该病通常影响亚裔、女性及老年人。患者通常表现为非酮症性高血糖所致的偏身投掷症 - 偏身舞蹈症。偏身投掷症 - 偏身舞蹈症被定义为累及身体一侧的不自主连续随机出现的运动。这种运动障碍可能继发于中风、糖尿病性纹状体病、肿瘤、感染、威尔逊病及甲状腺毒症。尽管罕见,但及时识别高血糖诱发的偏身投掷症 - 偏身舞蹈症至关重要,因为随着高血糖的纠正症状是可逆的。基于血液分析和神经影像学检查结果可做出诊断。实验室检查显示血糖和糖化血红蛋白水平升高,这表明糖尿病控制不佳。神经影像学检查可提供糖尿病性纹状体病的提示性表现,即计算机断层扫描显示基底节区高密度影,T1加权磁共振成像显示高信号。在本病例报告中,我们旨在呈现一名成年男性突发与非酮症性高血糖相关的偏身投掷症的神经影像学检查结果。