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糖尿病性纹状体病伴两次偏侧舞蹈症-偏侧投掷症综合征的磁共振成像容积分析:病例报告

Magnetic resonance imaging volumetric analysis for diabetic striatopathy with two episodes of hemichorea-hemiballism syndrome: A case report.

作者信息

Lin Yi-Te, Chen Shih-Chung, Yip Ping-Keung, Wang Vinchi

机构信息

Department of Neurology, Cardinal Tien Hospital.

School of Medicine, College of Medicine, Fu-Jen Catholic University.

出版信息

Medicine (Baltimore). 2019 Sep;98(38):e17249. doi: 10.1097/MD.0000000000017249.

Abstract

RATIONALE

Diabetic striatopathy (DS) is an uncommon movement disorder among diabetic patients characterized by clinical hemichorea-hemiballism with neuroimage change of the striatum. Here, we report a case of DS with relapsed hemichorea-hemiballism attacks even during euglycemic period, and the MRI changes by volumetric analysis.

PATIENT CONCERNS

A 69-year-old diabetic female suffered from a relapsed episode of hemichorea-hemiballism during her euglycemic period after the treatment of hyperglycemia.

DIAGNOSES

To investigate the serial MRI changes in a case with diabetic striatopathy who had clinical hemichorea-hemiballism syndrome.

INTERVENTIONS

Semi-quantitative volumetric analyses from T1 images of these brain MRIs were obtained during the disease course.

OUTCOMES

Besides, the negative finding of the first brain MRI during her first hospital admission, three afterward MRI examinations disclosed a waxing-and-waning mode of volume change from high-signal T1 images in left striatum. The clinical symptoms paralleled with the neuroimage changes in striatum. The MR signal volume changes were valuable for the clinical course of the hemichorea-hemiballism caused by diabetic striatopathy LESSONS:: Serial MR images for the diabetic striatopathy presented as a key pathognomonic relationship with the clinical hemichorea-hemiballism syndrome, assessed by our simplied volumetric analysis. Clinical involuntary movements may relapse and persist even with euglycemic condition as our case.

摘要

原理

糖尿病性纹状体病(DS)是糖尿病患者中一种罕见的运动障碍,其特征为临床出现偏侧舞蹈症-偏侧投掷症,同时纹状体有神经影像学改变。在此,我们报告一例即使在血糖正常期仍有复发性偏侧舞蹈症-偏侧投掷症发作的糖尿病性纹状体病病例,以及通过体积分析得出的MRI变化。

患者情况

一名69岁的糖尿病女性在高血糖治疗后血糖正常期出现了偏侧舞蹈症-偏侧投掷症的复发。

诊断

为研究一例患有临床偏侧舞蹈症-偏侧投掷症综合征的糖尿病性纹状体病患者的系列MRI变化。

干预措施

在病程中获取这些脑部MRI的T1图像进行半定量体积分析。

结果

此外,首次入院时的首次脑部MRI检查结果为阴性,随后的三次MRI检查显示左侧纹状体T1高信号图像的体积变化呈增减模式。临床症状与纹状体的神经影像学变化平行。MR信号体积变化对糖尿病性纹状体病所致偏侧舞蹈症-偏侧投掷症的临床病程具有重要意义。经验教训:通过我们简化的体积分析评估,糖尿病性纹状体病的系列MR图像与临床偏侧舞蹈症-偏侧投掷症综合征呈现出关键的特征性关系。正如我们的病例所示,即使血糖正常,临床不自主运动仍可能复发并持续存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90af/6756614/f7ebec1f9cba/medi-98-e17249-g001.jpg

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