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Fractional flow reserve and myocardial perfusion by computed tomography: a guide to clinical application.冠状动脉血流储备分数和计算机断层扫描心肌灌注：临床应用指南。
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Quantification of myocardial blood flow by adenosine-stress CT perfusion imaging in pigs during various degrees of stenosis correlates well with coronary artery blood flow and fractional flow reserve.腺苷负荷 CT 灌注成像定量检测不同狭窄程度猪心肌血流量与冠状动脉血流和血流储备分数相关性良好。
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本文引用的文献

1
Absolute Versus Relative Myocardial Blood Flow by Dynamic CT Myocardial Perfusion Imaging in Patients With Anatomic Coronary Artery Disease.动态CT心肌灌注成像评估解剖性冠状动脉疾病患者的绝对与相对心肌血流
AJR Am J Roentgenol. 2015 Jul;205(1):W67-72. doi: 10.2214/AJR.14.14087.
2
A randomized, multicenter, multivendor study of myocardial perfusion imaging with regadenoson CT perfusion vs single photon emission CT.随机、多中心、多供应商的瑞加德松 CT 灌注心肌灌注成像与单光子发射 CT 研究。
J Cardiovasc Comput Tomogr. 2015 Mar-Apr;9(2):103-12.e1-2. doi: 10.1016/j.jcct.2015.01.002. Epub 2015 Jan 7.
3
Diagnostic accuracy of stress myocardial perfusion imaging compared to invasive coronary angiography with fractional flow reserve meta-analysis.压力心肌灌注成像与有创冠状动脉造影术伴血流储备分数的荟萃分析比较的诊断准确性。
Circ Cardiovasc Imaging. 2015 Jan;8(1). doi: 10.1161/CIRCIMAGING.114.002666.
4
Relative flow reserve derived from quantitative perfusion imaging may not outperform stress myocardial blood flow for identification of hemodynamically significant coronary artery disease.定量灌注成像衍生的相对血流储备可能不如应激心肌血流，无法用于明确有血流动力学意义的冠状动脉疾病。
Circ Cardiovasc Imaging. 2015 Jan;8(1). doi: 10.1161/CIRCIMAGING.114.002400.
5
Dynamic CT myocardial perfusion measurements of resting and hyperaemic blood flow in low-risk subjects with 128-slice dual-source CT.采用128层双源CT对低风险受试者静息和充血状态下的心肌血流进行动态CT心肌灌注测量。
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):300-6. doi: 10.1093/ehjci/jeu200. Epub 2014 Nov 6.
6
Relative myocardial blood flow by dynamic computed tomographic perfusion imaging predicts hemodynamic significance of coronary stenosis better than absolute blood flow.通过动态计算机断层扫描灌注成像获得的相对心肌血流量比绝对血流量能更好地预测冠状动脉狭窄的血流动力学意义。
Invest Radiol. 2014 Dec;49(12):801-7. doi: 10.1097/RLI.0000000000000087.
7
Incremental value of pharmacological stress cardiac dual-energy CT over coronary CT angiography alone for the assessment of coronary artery disease in a high-risk population.药物负荷心脏双能 CT 相对于单独冠状动脉 CT 血管造影在高危人群中评估冠状动脉疾病的增量价值。
AJR Am J Roentgenol. 2014 Jul;203(1):W70-7. doi: 10.2214/AJR.13.11772.
8
Myocardial CT perfusion imaging and SPECT for the diagnosis of coronary artery disease: a head-to-head comparison from the CORE320 multicenter diagnostic performance study.心肌 CT 灌注成像与 SPECT 诊断冠状动脉疾病：来自 CORE320 多中心诊断性能研究的头对头比较。
Radiology. 2014 Aug;272(2):407-16. doi: 10.1148/radiol.14140806. Epub 2014 May 26.
9
Normal range and regional heterogeneity of myocardial perfusion in healthy human myocardium: assessment on dynamic perfusion CT using 128-slice dual-source CT.正常范围和健康人心肌的区域性异质性：使用 128 层双源 CT 进行动态灌注 CT 评估。
Int J Cardiovasc Imaging. 2014 Jun;30 Suppl 1:33-40. doi: 10.1007/s10554-014-0432-x. Epub 2014 May 3.
10
Effects of sex on coronary microvascular dysfunction and cardiac outcomes.性别对冠状动脉微血管功能障碍和心脏结局的影响。
Circulation. 2014 Jun 17;129(24):2518-27. doi: 10.1161/CIRCULATIONAHA.113.008507. Epub 2014 Apr 30.

通过计算机断层扫描对心肌灌注进行静态和动态评估。

Static and dynamic assessment of myocardial perfusion by computed tomography.

作者信息

Danad Ibrahim, Szymonifka Jackie, Schulman-Marcus Joshua, Min James K

机构信息

NewYork-Presbyterian Hospital and Weill Cornell Medicine, 413 E. 69th Street, Suite 108, New York 10021, NY, USA Dalio Institute of Cardiovascular Imaging, New York, NY, USA.

NewYork-Presbyterian Hospital and Weill Cornell Medicine, 413 E. 69th Street, Suite 108, New York 10021, NY, USA Dalio Institute of Cardiovascular Imaging, New York, NY, USA

出版信息

Eur Heart J Cardiovasc Imaging. 2016 Aug;17(8):836-44. doi: 10.1093/ehjci/jew044. Epub 2016 Mar 24.

DOI:10.1093/ehjci/jew044
PMID:27013250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4955293/
Abstract

Recent developments in computed tomography (CT) technology have fulfilled the prerequisites for the clinical application of myocardial CT perfusion (CTP) imaging. The evaluation of myocardial perfusion by CT can be achieved by static or dynamic scan acquisitions. Although both approaches have proved clinically feasible, substantial barriers need to be overcome before its routine clinical application. The current review provides an outline of the current status of CTP imaging and also focuses on disparities between static and dynamic CTPs for the evaluation of myocardial blood flow.

摘要

计算机断层扫描（CT）技术的最新进展满足了心肌CT灌注（CTP）成像临床应用的前提条件。通过静态或动态扫描采集可实现CT对心肌灌注的评估。尽管这两种方法在临床上均已证明可行，但在其常规临床应用之前仍需克服诸多重大障碍。本综述概述了CTP成像的现状，并着重探讨了静态和动态CTP在评估心肌血流方面的差异。