Johns M E, Goldsmith M M
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions.
Oncology (Williston Park). 1989 Feb;3(2):47-56; discussion 56, 58, 62.
The diagnosis of salivary gland tumors is complicated by their relative infrequency, the limited amount of pretreatment information usually available, and the wide range of biologic behaviors seen with different histopathologic types. Most salivary gland neoplasms originate in the parotid, 10-15% arise from the submandibular glands, and the rest occur in the sublingual and minor salivary glands. The probability of a salivary gland neoplasm being malignant is inversely proportional to the size of the gland. The authors discuss two major theories of histogenesis, itemize the various benign and malignant varieties of tumor, discuss the presentation and prognosis for each type, and present a list of factors that influence survival. They also discuss the newest staging system.
唾液腺肿瘤的诊断较为复杂，原因在于其相对少见、通常可获得的预处理信息有限，以及不同组织病理学类型所呈现出的广泛生物学行为。大多数唾液腺肿瘤起源于腮腺，10% - 15%起源于颌下腺，其余发生于舌下腺和小唾液腺。唾液腺肿瘤为恶性的概率与腺体大小成反比。作者讨论了两种主要的组织发生学理论，列举了各种良性和恶性肿瘤类型，讨论了每种类型的临床表现和预后，并列出了影响生存的因素清单。他们还讨论了最新的分期系统。
