Li Cai-Ying, Gao Bu-Lang, Guo Fu-Qian, Zhang Xue-Jing, Fan Qiong-Ying, Wu Bai-Lin, Xiang Cheng, Liu Xiao-Wei, Pan Tong
Department of Medical Imaging, Second Hospital, Hebei Medical University, Hebei, China.
Department of Medical Research, Shijiazhuang First Hospital, Hebei Medical University, Hebei, China.
J Magn Reson Imaging. 2016 Nov;44(5):1143-1150. doi: 10.1002/jmri.25243. Epub 2016 Mar 26.
To quantitatively investigate left ventricular volume and function in middle-aged healthy subjects.
Ninety healthy volunteers underwent cardiac 3 Tesla MRI. The left ventricular end-diastolic volume (EDV) and end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), cardiac output (CO), myocardial mass (MM), and their normalized indices (EDVI, ESVI, SVI, CI, and MI, respectively) after corrected with the body surface area (BSA) were analyzed and compared at different ages.
All subjects had successfully completed the 3-Tesla cardiac MR. Females had significantly smaller EDV (110.5 ± 9.2 versus 125.7 ± 8.3 mL), ESV (36.1 ± 3.5 versus 41.5 ± 3.8 mL), SV (74.3 ± 6.3 versus 84.2 ± 6.7 mL), CO (5.4 ± 0.8 versus 5.8 ± 0.9 l/min) and MM (73.0 ± 10.5 versus 94.8 ± 10.6 g) than males (P < 0.05). The EF had no significant (P = 0.47) difference between genders (67.3 ± 1.7 percent in females versus 66.9 ± 2.4 percent in males). After normalization with BSA, no significant (P > 0.05) difference was detected between the genders in EDVI (71.2 ± 4.3 versus 71.1 ± 4.2 mL/m , P = 0.882), ESVI (23.3 ± 1.9 versus 23.5 ± 1.9 mL/m , P = 0.733) and SVI (47.9 ± 2.9 versus 47.7 ± 3.7 mL/m , P = 0.698) except for CI and MI. Females had significantly (P < 0.05) greater CI (3.5 ± 0.4 versus 3.3 ± 0.4) but smaller MI (46.9 ± 5.3 versus 53.6 ± 7.6) than males. EDV, EDVI, ESV, ESVI, SV, and SVI significantly (P < 0.05) decreased with age increase. BSA was positively correlated with EDV, ESV, SV, MM, and CO. No significance (P > 0.05) was detected in other parameters.
The left ventricular volume and function differs in women compared with men in the middle-aged population, and these parameters have a tendency of decrease with ageing. J. Magn. Reson. Imaging 2016;44:1143-1150.
定量研究中年健康受试者的左心室容积和功能。
90名健康志愿者接受了心脏3特斯拉磁共振成像检查。分析并比较了不同年龄组受试者的左心室舒张末期容积（EDV）、收缩末期容积（ESV）、每搏输出量（SV）、射血分数（EF）、心输出量（CO）、心肌质量（MM）及其经体表面积（BSA）校正后的标准化指标（分别为EDVI、ESVI、SVI、CI和MI）。
所有受试者均成功完成3特斯拉心脏磁共振成像检查。女性的EDV（110.5±9.2对125.7±8.3 mL）、ESV（36.1±3.5对41.5±3.8 mL）、SV（74.3±6.3对84.2±6.7 mL）、CO（5.4±0.8对5.8±0.9 l/min）和MM（73.0±10.5对94.8±10.6 g）均显著小于男性（P<0.05）。EF在性别之间无显著差异（P = 0.47）（女性为67.3±1.7%，男性为66.9±2.4%）。经BSA标准化后，除CI和MI外，EDVI（71.2±4.3对71.1±4.2 mL/m²，P = 0.882）、ESVI（23.3±1.9对23.5±1.9 mL/m²，P = 0.733）和SVI（47.9±2.9对47.7±3.7 mL/m²，P = 0.698）在性别之间未检测到显著差异（P>0.05）。女性的CI显著高于男性（P<0.05）（3.5±0.4对3.3±0.4），但MI低于男性（46.9±5.3对53.6±7.6）。EDV、EDVI、ESV、ESVI、SV和SVI随年龄增长显著降低（P<0.05）。BSA与EDV、ESV、SV、MM和CO呈正相关。其他参数未检测到显著差异（P>0.05）。
中年人群中，女性与男性的左心室容积和功能存在差异，且这些参数有随年龄增长而降低的趋势。《磁共振成像杂志》2016年；44：1143 - 1150。
