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New derivatives of 5-nitroimidazole: synthesis and antiparasitic activity.

作者信息

Alcalde E, Maños L, Dinares I, Valls N, Elguero J, Escario J A, Martinez A R, Igea A, Osuna A, Ruiz-Perez L M

机构信息

Lab. Quimica Organica, Facultad de Farmacia, Universidad de Barcelona, España.

出版信息

Farmaco. 1989 Nov;44(11):1095-107.

PMID:2701965
Abstract

The synthesis and the antiparasitic evaluation of twelve new 5-nitroimidaole derivatives has been carried out. The most effective compounds were the less hydrophilic pyridinium and imidazolium salts (IV), (V) and (X), and above all the tetrahydropyridine derivatives (XII) and (XIII).

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