John Seby, Stock Sarah, Masaryk Thomas, Bauer Andrew, Cerejo Russell, Uchino Ken, Winners Stacey, Rasmussen Peter, Hussain Muhammad S
Cerebrovascular Center, Cleveland Clinic, Cleveland, OH.
Department of Neuroradiology, Cleveland Clinic, Cleveland, OH.
J Neuroimaging. 2016 Jul;26(4):391-4. doi: 10.1111/jon.12346. Epub 2016 Mar 30.
There is a strong inverse relationship between outcome in patients with acute ischemic stroke from emergent large vessel occlusion (ELVO), and time to reperfusion from intra-arterial therapy. Delay in transferring patients to thrombectomy-capable centers is currently a major limitation. The mobile stroke unit (MSU) concept with onboard portable computed tomography (CT) scanner enables rapid performance of CT angiography (CTA) of the intracranial vessels to detect ELVO in the field, and allows for rapid triage of patients to interventional-capable centers.
Our institution implemented a mobile stroke treatment unit (MSTU) program that started on July 2014, and CTA capability was added on April 2015. The eligibility criteria, equipment, and method of CTA imaging are described. We report the first case of CTA being performed in the field in the United States to aid in triage of ELVO patients.
MSTU was dispatched for reported new onset of right hemiparesis in a patient. Teleneurological assessment detected findings consistent with a severe left middle cerebral artery (MCA) syndrome. Noncontrast CT head revealed left lenticulostriate hypoattenuation. A CTA was performed subsequently on the MSTU that showed an MCA cutoff. Based on these findings, patient was immediately transferred to the main hospital with neurointerventional capability, where he underwent successful recanalization with improvement in symptoms.
CTA is possible on an MSTU, enabling rapid detection and triage of ELVO cases directly to thrombectomy-capable centers, which significantly reduces time to endovascular treatment.
急性缺血性卒中伴紧急大血管闭塞(ELVO)患者的预后与动脉内治疗的再灌注时间之间存在强烈的负相关关系。目前,将患者转运至具备血栓切除术能力的中心存在延迟是一个主要限制因素。配备车载便携式计算机断层扫描(CT)扫描仪的移动卒中单元(MSU)概念能够在现场快速进行颅内血管的CT血管造影(CTA)以检测ELVO,并允许将患者快速分诊至具备介入治疗能力的中心。
我们机构于2014年7月启动了移动卒中治疗单元(MSTU)项目,并于2015年4月增加了CTA功能。描述了CTA成像的入选标准、设备和方法。我们报告了美国首例在现场进行CTA以协助ELVO患者分诊的病例。
MSTU被派往一名报告出现新的右侧偏瘫的患者处。远程神经学评估发现与严重的左侧大脑中动脉(MCA)综合征相符的表现。非增强头部CT显示左侧豆纹状核低密度。随后在MSTU上进行了CTA,显示MCA闭塞。基于这些发现,患者立即被转至具备神经介入能力的主医院,在那里他接受了成功的再通治疗,症状得到改善。
在MSTU上进行CTA是可行的,能够直接快速检测和分诊ELVO病例至具备血栓切除术能力的中心,这显著缩短了血管内治疗的时间。