Haffner S M, Hazuda H P, Stern M P, Patterson J K, Van Heuven W A, Fong D
Department of Medicine, University of Texas Health Science Center, San Antonio 78284.
Diabetes Care. 1989 Feb;12(2):128-34. doi: 10.2337/diacare.12.2.128.
Mexican Americans have a threefold greater prevalence of non-insulin-dependent diabetes mellitus (NIDDM) than non-Hispanic Whites. Moreover, Mexican-American diabetic people have more severe hyperglycemia and diabetic retinopathy than non-Hispanic White diabetic people. Mexican Americans are predominantly of low socioeconomic status (SES), and low-SES Mexican Americans have a higher prevalence of NIDDM than higher-SES Mexican Americans. Therefore, we hypothesized that among diabetic people, low SES would be associated with more severe hyperglycemia and retinopathy. Three hundred forty-three Mexican Americans and 79 non-Hispanic Whites with NIDDM were identified from the San Antonio Heart Study, a population-based study of diabetes and cardiovascular disease. Hyperglycemia was assessed as the sum of the fasting, 1-h, and 2-h plasma glucose concentrations during a standard oral glucose tolerance test. Retinopathy was assessed by 7 standard stereoretinal photographs. SES was assessed with three indicators: Duncan's socioeconomic index, education, and income. Contrary to expectations, low SES was not associated with greater levels of hyperglycemia or grades of retinopathy.
墨西哥裔美国人患非胰岛素依赖型糖尿病(NIDDM)的患病率是非西班牙裔白人的三倍。此外,墨西哥裔美国糖尿病患者比非西班牙裔白人糖尿病患者有更严重的高血糖和糖尿病视网膜病变。墨西哥裔美国人主要社会经济地位(SES)较低,社会经济地位低的墨西哥裔美国人患NIDDM的患病率高于社会经济地位高的墨西哥裔美国人。因此,我们假设在糖尿病患者中,低社会经济地位会与更严重的高血糖和视网膜病变相关。从圣安东尼奥心脏研究中确定了343名患有NIDDM的墨西哥裔美国人和79名非西班牙裔白人,这是一项基于人群的糖尿病和心血管疾病研究。高血糖通过标准口服葡萄糖耐量试验期间的空腹、1小时和2小时血浆葡萄糖浓度总和进行评估。视网膜病变通过7张标准立体视网膜照片进行评估。社会经济地位用三个指标进行评估:邓肯社会经济指数、教育程度和收入。与预期相反,低社会经济地位与更高水平的高血糖或视网膜病变分级无关。