El Amrani Mehdi, Pruvot François-René, Truant Stéphanie
Department of Digestive Surgery and Transplantation, CHRU de Lille, Lille, France.
J Gastrointest Oncol. 2016 Apr;7(2):298-305. doi: 10.3978/j.issn.2078-6891.2015.093.
The right hepatic artery (RHA) is the most common hepatic artery (CHA) variation. This variation may be problematic in pancreaticoduodenectomy (PD). We aimed to evaluate the impact of the RHA on postoperative and oncological outcomes.
The PubMed database was systematically searched for comparative studies reporting management of the RHA during PD for the years 1950-2014.
A total of 2,278 patients were analyzed, of whom 440 (19%) had a RHA. The most CHA variation was a replaced RHA. The conservative approach was the most frequently adopted (87%) and only 8% of patients had a sacrifice without reconstruction of the RHA. Postoperative mortality and overall morbidity were similar between patients with and without RHA. Despite the preservation of the RHA in most cases, the rates of microscopic positive margin were also comparable between two groups with no impact of RHA on survival rates.
Postoperative and oncological outcomes seemed unaffected by the RHA in PD. Prospective studies are needed to evaluate its oncological impact.
右肝动脉(RHA)是肝动脉(CHA)最常见的变异。这种变异在胰十二指肠切除术(PD)中可能会产生问题。我们旨在评估RHA对术后及肿瘤学结局的影响。
系统检索PubMed数据库,查找1950年至2014年期间报告PD术中RHA处理的比较研究。
共分析了2278例患者,其中440例(19%)存在RHA。最常见的CHA变异是替代RHA。最常采用的是保守方法(87%),仅有8%的患者在未重建RHA的情况下进行了牺牲。有RHA和无RHA的患者术后死亡率和总体发病率相似。尽管在大多数情况下保留了RHA,但两组的显微镜下切缘阳性率也相当,RHA对生存率无影响。
PD中RHA似乎不影响术后及肿瘤学结局。需要进行前瞻性研究以评估其对肿瘤学的影响。