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一种新的钛基合金 Ti-27Nb-13Zr,通过粉末冶金制造,具有仿生涂层,可用作生物材料。

A new titanium based alloy Ti-27Nb-13Zr produced by powder metallurgy with biomimetic coating for use as a biomaterial.

机构信息

Materials Science and Technology Center, Energy and Nuclear Research Institute, Av. Lineu Prestes 2242, C.P: 05508-000 São Paulo, SP, Brazil.

Materials Science and Technology Center, Energy and Nuclear Research Institute, Av. Lineu Prestes 2242, C.P: 05508-000 São Paulo, SP, Brazil.

出版信息

Mater Sci Eng C Mater Biol Appl. 2016 Jun;63:671-7. doi: 10.1016/j.msec.2016.03.052. Epub 2016 Mar 17.

Abstract

Titanium alloys are widely used in biomedical applications due to their excellent properties such as high strength, good corrosion resistance and biocompatibility. Titanium alloys with alloying elements such as Nb and Zr are biocompatible and have Young's modulus close to that of human bone. To increase the bioactivity of titanium alloy surfaces is used chemical treatment with NaOH followed by immersion in simulated body fluid (SBF). The purpose of this study was to produce the alloy Ti-27Nb-13Zr with low Young's modulus by powder metallurgy using powders produced by the HDH process. The formation of biomimetic coatings on samples immersed in SBF for 3, 7, 11 and 15 days was evaluated. Characterization of the coating was performed by diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) and scanning electron microscope. The microstructure and composition of the alloy were determined using SEM and XRD, while the mechanical properties were evaluated by determining the elastic modulus and the Vickers microhardness. The sintered alloys were composed of α and β phases, equiaxed grains and with density around 97.8% of its theoretical density. The Vickers microhardness and elasticity modulus of the alloy were determined and their values indicate that this alloy can be used as a biomaterial. Analysis of the coating revealed the presence of calcium phosphate layers on samples immersed for >3 days in the SBF solution.

摘要

钛合金由于其高强度、良好的耐腐蚀性和生物相容性等优异性能,被广泛应用于生物医学领域。添加 Nb 和 Zr 等合金元素的钛合金具有生物相容性,其杨氏模量接近人体骨骼。为了提高钛合金表面的生物活性,采用了 NaOH 化学处理,然后将其浸泡在模拟体液(SBF)中。本研究的目的是通过使用 HDH 工艺生产的粉末,采用粉末冶金法生产出杨氏模量低的 Ti-27Nb-13Zr 合金。评价了在 SBF 中浸泡 3、7、11 和 15 天的样品上仿生涂层的形成。通过漫反射红外傅里叶变换光谱(DRIFTS)和扫描电子显微镜对涂层进行了表征。采用 SEM 和 XRD 确定了合金的微观结构和组成,通过测定弹性模量和维氏显微硬度评估了合金的力学性能。烧结合金由α和β相、等轴晶粒组成,密度约为其理论密度的 97.8%。测定了合金的维氏硬度和弹性模量,其值表明该合金可用作生物材料。对涂层的分析表明,在 SBF 溶液中浸泡>3 天的样品表面存在磷酸钙层。

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