Barasheed Osamah, Alfelali Mohammad, Mushta Sami, Bokhary Hamid, Alshehri Jassir, Attar Ammar A, Booy Robert, Rashid Harunor
Research Center, King Abdullah Medical City (KAMC), Makkah, P.O. Box: 57657, Saudi Arabia; National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases (NCIRS), The Children's Hospital at Westmead, NSW, Australia.
National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases (NCIRS), The Children's Hospital at Westmead, NSW, Australia; Department of Family and Community Medicine, Faculty of Medicine, King Abdulaziz University, Rabigh, Saudi Arabia.
Int J Infect Dis. 2016 Jun;47:105-11. doi: 10.1016/j.ijid.2016.03.023. Epub 2016 Mar 29.
The risk of acquisition and transmission of respiratory infections is high among attendees of mass gatherings (MGs). Currently used interventions have limitations yet the role of facemask in preventing those infections at MG has not been systematically reviewed. We have conducted a systematic review to synthesise evidence about the uptake and effectiveness of facemask against respiratory infections in MGs.
A comprehensive literature search was conducted according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines using major electronic databases such as, Medline, EMBASE, SCOPUS and CINAHL.
Of 25 studies included, the pooled sample size was 12710 participants from 55 countries aged 11 to 89 years, 37% were female. The overall uptake of facemask ranged from 0.02% to 92.8% with an average of about 50%. Only 13 studies examined the effectiveness of facemask, and their pooled estimate revealed significant protectiveness against respiratory infections (relative risk [RR]=0.89, 95% CI: 0.84-0.94, p<0.01), but the study end points varied widely.
A modest proportion of attendees of MGs use facemask, the practice is more widespread among health care workers. Facemask use seems to be beneficial against certain respiratory infections at MGs but its effectiveness against specific infection remains unproven.
在大型集会（MGs）的参与者中，呼吸道感染的获得和传播风险很高。目前使用的干预措施存在局限性，但口罩在MGs预防此类感染中的作用尚未得到系统评价。我们进行了一项系统评价，以综合关于口罩在MGs中预防呼吸道感染的使用情况和有效性的证据。
根据系统评价和Meta分析的首选报告项目（PRISMA）指南，使用主要电子数据库，如Medline、EMBASE、SCOPUS和CINAHL，进行全面的文献检索。
纳入的25项研究中，汇总样本量为来自55个国家的12710名参与者，年龄在11至89岁之间，37%为女性。口罩的总体使用率从0.02%到92.8%不等，平均约为50%。只有13项研究检验了口罩的有效性，其汇总估计显示对呼吸道感染有显著的保护作用（相对风险[RR]=0.89，95%CI：0.84-0.94，p<0.01），但研究终点差异很大。
MGs的参与者中使用口罩的比例适中，这种做法在医护人员中更为普遍。在MGs中使用口罩似乎对某些呼吸道感染有益，但其对特定感染的有效性仍未得到证实。
