利用磁粒子成像系统对磁性装置进行操控

Steering of Magnetic Devices With a Magnetic Particle Imaging System.

作者信息

Nothnagel Nils, Rahmer Jurgen, Gleich Bernhard, Halkola Aleksi, Buzug Thorsten M, Borgert Jorn

出版信息

IEEE Trans Biomed Eng. 2016 Nov;63(11):2286-2293. doi: 10.1109/TBME.2016.2524070. Epub 2016 Feb 2.

Abstract

Small magnetic devices have been steered in arbitrary direction and with variable force using a preclinical demonstrator system for magnetic particle imaging (MPI). Fast localization due to the high imaging rate of over 40 volumes/s and strong forces due to the high field gradient of more than 1 T/m render an MPI system, a good platform for image-guided steering of magnetic devices. In this paper, these capabilities are demonstrated in phantom experiments, where a closed feedback loop has been realized to exert translational forces in horizontal and vertical direction on a magnetic device moving in a viscous medium. The MPI system allows for the controlled application of those forces by combining variable homogeneous fields with strong field gradients.

摘要

使用用于磁粒子成像(MPI)的临床前演示系统,小型磁性装置已被引导至任意方向,并以可变力进行操控。由于超过40体素/秒的高成像速率实现了快速定位,以及超过1 T/m的高场梯度产生了强大的力,使得MPI系统成为用于磁性装置图像引导操控的良好平台。在本文中,这些能力在体模实验中得到了证明,其中实现了一个封闭反馈回路,以在粘性介质中移动的磁性装置上施加水平和垂直方向的平移力。MPI系统通过将可变均匀场与强场梯度相结合,实现了对这些力的可控应用。

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