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埃塞俄比亚西北部帕韦医院儿童中与恶性疟原虫和间日疟原虫相关的严重疟疾

Severe Malaria Associated with Plasmodium falciparum and P. vivax among Children in Pawe Hospital, Northwest Ethiopia.

作者信息

Geleta Getachew, Ketema Tsige

机构信息

Department of Biology, College of Natural Sciences, Jimma University, P.O. Box 378, Jimma, Ethiopia.

出版信息

Malar Res Treat. 2016;2016:1240962. doi: 10.1155/2016/1240962. Epub 2016 Mar 7.

Abstract

Despite rigorous effort made to control malaria for more than a century, it is still among the main public health problems in least developed regions of the world. Majority of deaths associated with malaria occur in sub-Sahara Africa among biologically risked groups. Thus, this study was designed to assess the incidence of severe malaria syndromes among children in Pawe Hospital, Northwest Ethiopia. Children seeking medication for malaria infection in Pawe Hospital during the study period were recruited. Sociodemographic characteristics, physical, hematological, and clinical features of complicated malaria were assessed following standard parasitological and clinical procedures. A total of 263 children were found malaria positive. Among these, 200 were infected with Plasmodium falciparum. Most of the severe malaria symptoms were observed among children infected with P. falciparum and P. vivax. The study showed that significant number of the children developed severe life threatening malaria complications. This calls for prompt early diagnosis and effective treatment of patients to reduce mortality and complications associated with malaria in the study site.

摘要

尽管在一个多世纪里为控制疟疾付出了巨大努力,但它仍是世界最不发达地区主要的公共卫生问题之一。与疟疾相关的死亡大多发生在撒哈拉以南非洲生物风险较高的人群中。因此,本研究旨在评估埃塞俄比亚西北部帕韦医院儿童中重症疟疾综合征的发病率。研究期间在帕韦医院寻求疟疾感染治疗的儿童被招募进来。按照标准的寄生虫学和临床程序评估复杂疟疾的社会人口统计学特征、身体、血液学和临床特征。共发现263名儿童疟疾检测呈阳性。其中,200名感染了恶性疟原虫。大多数重症疟疾症状出现在感染恶性疟原虫和间日疟原虫的儿童中。研究表明,相当数量的儿童出现了严重危及生命的疟疾并发症。这就要求对患者进行及时的早期诊断和有效治疗,以降低研究地点与疟疾相关的死亡率和并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178b/4800101/95e7547a2206/MRT2016-1240962.001.jpg

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