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HIV感染患者的股骨头缺血性坏死:陶瓷对陶瓷关节置换手术治疗的初步结果

AVASCULAR NECROSIS OF THE FEMORAL HEAD IN HIV-INFECTED PATIENTS: PRELIMINARY RESULTS FROM SURGICAL TREATMENT FOR CERAMIC-CERAMIC JOINT REPLACEMENT.

作者信息

Cabrita Henrique Amorim, Santos Alexandre Leme de Godoy, Gobbi Riccardo Gomes, Lima Ana Lúcia Munhoz, Oliveira Priscila Rosalba, Ejnisman Leandro, Gurgel Henrique Melo Campos, Uip David, Camanho Gilberto Luis

机构信息

Attending Physician in the Hip Group, Institute of Orthopedics and Traumatology, HC/FMUSP, São Paulo, Brazil.

Attending Physician in the Foot and Ankle Group and in the Trauma Group, Institute of Orthopedics and Traumatology, HC/FMUSP, São Paulo, Brazil.

出版信息

Rev Bras Ortop. 2015 Nov 4;47(5):626-30. doi: 10.1016/S2255-4971(15)30014-8. eCollection 2012 Sep-Oct.

Abstract

OBJECTIVES

To evaluate the initial functional results and early complication rate of ceramic-ceramic total hip replacements among patients living with HIV who presented osteonecrosis of the femoral head.

METHOD

Twelve HIV-positive patients with a diagnosis of osteonecrosis of the incongruent femoral head were evaluated using clinical and laboratory criteria and the WOMAC functional scale before and after treatment with joint replacement.

RESULTS

We observed that 83.3% of the subjects were taking protease inhibitors, 75% had dyslipidemia and 66.6% had lipodystrophy syndrome. The improvement over the evolution of the WOMAC score was statistically significant at six and twelve months after the operation, in comparison with the preoperative score. We did not observe complications secondary to this procedure.

CONCLUSION

Total hip arthroplasty with a ceramic-ceramic implant for treating avascular necrosis of the hip is an appropriate surgical option for this portion of the population. It provides a significant initial functional improvement and a low early complication rate.

摘要

目的

评估股骨头坏死的HIV感染者接受陶瓷对陶瓷全髋关节置换术后的早期功能结果和早期并发症发生率。

方法

采用临床和实验室标准以及WOMAC功能量表,对12例诊断为股骨头坏死且股骨头不协调的HIV阳性患者在关节置换治疗前后进行评估。

结果

我们观察到83.3%的受试者正在服用蛋白酶抑制剂,75%患有血脂异常,66.6%患有脂肪代谢障碍综合征。与术前评分相比,术后6个月和12个月时WOMAC评分的改善具有统计学意义。我们未观察到该手术继发的并发症。

结论

对于这部分人群,采用陶瓷对陶瓷植入物进行全髋关节置换术治疗髋关节缺血性坏死是一种合适的手术选择。它能带来显著的早期功能改善且早期并发症发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db55/4799464/ce0a2f865040/gr1.jpg

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