Trapp L D, Goodson J M, Price D C
J Dent Res. 1977 Aug;56(8):889-93. doi: 10.1177/00220345770560080801.
Oral submucosal blood flow was measured at dental injection sites in anesthetized dogs and compared with subcutaneous blood flow. Blood flow was calculated from the measured half-time for clearance of radioactive xenon dissolved in saline. By this method, oral submucosal blood flow was much greater than subcutaneous blood flow and was comparable in magnitude to values reported for cerebral blood flow. Injection of a solution containing 1:100,000 epinephrine at the mandibular canal produce a delayed clearance of isotope which was three times as long as the clearance time for solutions without epinephrine.
在麻醉犬的牙齿注射部位测量口腔黏膜下血流，并与皮下血流进行比较。血流是根据溶解在盐水中的放射性氙清除的测量半衰期计算得出的。通过这种方法，口腔黏膜下血流远大于皮下血流，其大小与报道的脑血流值相当。在下颌管注射含1:100,000肾上腺素的溶液会使同位素清除延迟，其时间是不含肾上腺素溶液清除时间的三倍。
