Mitrovic D
Rev Prat. 1989 Mar 2;39(7):551-4.
Although the frequency and severity of osteo-arthrosis regularly increase after the age of 50 years, individual's age does not seem to be a causal factor of this disorder. Indeed, osteoarthrosis does not affect all age individuals and not all joints are involved at the time. Various etiological factors (traumatisms, joint malformations and preexisting disorders, overuse of joints, etc.) are usually identified. Joint lesions in osteo-arthrosis are not those characteristic of senile involution, but rather represent proliferative reparative processes. Therefore, old age may act as one of the risk factors, which favors a development of osteo-arthrosis if others, more specific, etiological factors are present.
虽然骨关节炎的发病率和严重程度在50岁以后通常会增加，但个体年龄似乎并非这种疾病的致病因素。事实上，骨关节炎并非影响所有年龄段的个体，而且并非所有关节都会同时受累。通常可以确定各种病因（创伤、关节畸形和既往疾病、关节过度使用等）。骨关节炎中的关节病变并非老年退化的特征性病变，而是代表增殖性修复过程。因此，如果存在其他更具体的病因，老年可能作为一个危险因素，促使骨关节炎的发展。
