Chaudhary Shyam Chand, Nanda Satyan, Tripathi Adarsh, Sawlani Kamal Kumar, Gupta Kamlesh Kumar, Himanshu D, Verma Ajay Kumar
Department of General Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Lung India. 2016 Mar-Apr;33(2):174-8. doi: 10.4103/0970-2113.177441.
Psychiatric disorders, especially anxiety and depression have been reported to have an increased prevalence in chronic obstructive pulmonary disease (COPD) patients, but there is a paucity of data from India.
Aim of our study is to study the frequency of psychiatric comorbidities in COPD patients and their correlation with severity of COPD, as per global initiative for obstructive lung disease guidelines.
This study was conducted in outpatient department of a tertiary care hospital (King George's Medical University). A total of 74 COPD patients were included in this study and compared with 74 controls. The diagnosis and severity of COPD were assessed by spirometry. Psychiatric comorbidities were assessed using the Mini International Neuropsychiatric Interview questionnaire.
The frequency of psychiatric comorbidities was significantly higher (P < 0.05) in COPD patients (28.4%) as compared to controls (2.7%). As regards to severity, the frequency was significantly increased in severe and very severe COPD. The frequency of psychiatric comorbidities in COPD patients increased significantly with the increase in duration of symptoms being present in 67% of patients with duration of symptoms more than 10 years and only 23% of patients with duration of symptoms ≤5 years.
The frequency of psychiatric comorbidities is increased in COPD patients as compared to controls. We recommend that all patients with COPD should be screened for psychiatric comorbidity, if any.
据报道,慢性阻塞性肺疾病(COPD)患者中精神障碍,尤其是焦虑和抑郁的患病率有所增加,但来自印度的数据却很匮乏。
我们研究的目的是根据慢性阻塞性肺疾病全球倡议指南,研究COPD患者精神共病的发生率及其与COPD严重程度的相关性。
本研究在一家三级医疗医院(乔治国王医科大学)的门诊部进行。本研究共纳入74例COPD患者,并与74例对照进行比较。通过肺活量测定评估COPD的诊断和严重程度。使用迷你国际神经精神访谈问卷评估精神共病情况。
与对照组(2.7%)相比,COPD患者中精神共病的发生率显著更高(P < 0.05)(28.4%)。就严重程度而言,重度和极重度COPD患者的发生率显著增加。COPD患者精神共病的发生率随着症状持续时间的增加而显著增加,67%症状持续时间超过10年的患者有精神共病,而症状持续时间≤5年的患者中只有23%有精神共病。
与对照组相比,COPD患者精神共病的发生率增加。我们建议,所有COPD患者都应筛查是否存在精神共病。