Sridhara Venkata Sai Hari Kalyan, Acharya Vishak
Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Mangalore, Karnataka,India.
J Community Hosp Intern Med Perspect. 2021 Jan 26;11(1):120-123. doi: 10.1080/20009666.2020.1843823.
: COPD is an obstructive airway disease with significant systemic comorbidities that affect hospitalization and the overall severity of the disease. The aim of the study was to assess the prevalence of comorbidities and their effect on the hospitalization of COPD patients. : The study was a cross-sectional study conducted in 2013 among patients of a tertiary care hospital. The sample size was 106. Inclusion criteria were diagnosed patients of COPD according to GOLD criteria. Patients were diagnosed with COPD based on GOLD criteria guidelines and evaluated for various comorbidities based on presenting complaints. Variables collected were the number and kind of diagnosed comorbidities, the average number of hospitalizations per year. The prevalence of each comorbidity was found out and the chi-square test (p < 0.05) was used to find out the correlation between hospitalization and comorbidities. : Of 106 participants, 63.2% had at least 1 comorbidity. 37.73% had 2-4 comorbidities. Prevalence of diabetes mellitus was 35.8%, systemic hypertension was diagnosed in 47% of the subjects. 5.7% had left heart abnormalities, 4.7% had ischemic heart disease (IHD), and 16% had pulmonary arterial hypertension. 43.4% had gastroesophageal reflux disease and gastric ulceration, 38.6% had metabolic syndrome and 8.5% had obstructive sleep apnea, 8% had psychiatric disorders, 7.5% had osteoporosis, and 1.9% were diagnosed with lung malignancy. There was a significant association between mean hospitalizations and the presence of comorbidities (p < 0.05). Hospitalizations were majorly due to exacerbation of COPD. : Prevalence of comorbid conditions among COPD patients are concluded to be high with an adverse effect on the average number of hospitalizations per year.
慢性阻塞性肺疾病（COPD）是一种具有显著全身合并症的阻塞性气道疾病，这些合并症会影响住院情况和疾病的整体严重程度。本研究的目的是评估合并症的患病率及其对COPD患者住院情况的影响。：该研究是2013年在一家三级护理医院的患者中进行的横断面研究。样本量为106例。纳入标准是根据慢性阻塞性肺疾病全球倡议（GOLD）标准确诊的COPD患者。患者根据GOLD标准指南被诊断为COPD，并根据主诉评估各种合并症。收集的变量包括确诊合并症的数量和种类、每年的平均住院次数。计算每种合并症的患病率，并使用卡方检验（p<0.05）来确定住院与合并症之间的相关性。：在106名参与者中，63.2%至少有一种合并症。37.73%有2至4种合并症。糖尿病患病率为35.8%，47%的受试者被诊断为系统性高血压。5.7%有左心异常，4.7%有缺血性心脏病（IHD），16%有肺动脉高压。43.4%有胃食管反流病和胃溃疡，38.6%有代谢综合征，8.5%有阻塞性睡眠呼吸暂停，8%有精神障碍，7.5%有骨质疏松症，1.9%被诊断为肺癌。平均住院次数与合并症的存在之间存在显著关联（p<0.05）。住院主要是由于COPD急性加重。：得出结论，COPD患者中合并症的患病率很高，对每年的平均住院次数有不利影响。
