Johansson B B, Linder L E
Acta Neurol Scand. 1978 Apr;57(4):345-8. doi: 10.1111/j.1600-0404.1978.tb04508.x.
An acute hypertensive episode of short duration (less than 3 min) induced by i.v. injection of angiotensin in rats resulted in a blood-brain barrier dysfunction that was rapidly reversible. Thus, no macroscopic extravasation was seen when Evans blue was given 10 or 20 min after angiotensin. A faint fluorescence (Evans blue-albumin) was seen in the walls of some intracerebral arterioles in a few rats given the tracer 10 min after angiotensin.
通过静脉注射血管紧张素在大鼠中诱导的持续时间较短（少于3分钟）的急性高血压发作导致血脑屏障功能障碍，且该障碍可迅速逆转。因此，在注射血管紧张素后10或20分钟给予伊文思蓝时，未见明显的宏观外渗现象。在注射血管紧张素10分钟后给予示踪剂的少数大鼠中，在一些脑内小动脉壁中可见微弱荧光（伊文思蓝 - 白蛋白）。
