Lee Hyun Seung, Lee Chul Gab, Kim Dong Hun, Song Han Soo, Jung Min Soo, Kim Jae Yoon, Park Choong Hee, Ahn Seung Chul, Yu Seung Do
Department of Occupational & Environmental Medicine, School of Medicine, Chosun University, 558 Pilmun-daero, Dong-gu Gwangju, 61453 Korea.
Department of Radioloy, School of Medicine, Chosun University, 558 Pilmun-daero, Dong-gu Gwangju, 61453 Korea.
Ann Occup Environ Med. 2016 Apr 7;28:17. doi: 10.1186/s40557-016-0101-8. eCollection 2016.
To identify adverse pulmonary health effects due to air pollution derived from a cement plant in Korea. The emphysema prevalence in residents around a cement plant was compared to that in the group who live far away from the plant by chest films (PA and lateral view) and high-resolution computed tomography (HRCT) lung images.
From June to August in 2013 and from August to November in 2014, chest films and HRCT scan were conducted on residents over the age of 40 who lived around a cement plant. The residents were divided into two groups; a "more exposed group (MEG)" which consisted of 1,046 people who lived within a 1 km radius and a "less exposed group (LEG)" which consisted of 317 people who lived more than 5 km away from the same plant. We compared the emphysema prevalence and estimated the OR of this between the MEG and the LEG by using a chi-square and logistic regression on chest films and HRCT.
The emphysema prevalence was 9.1 % in the LEG, 14.3 % in the MEG on chest films and 11.4 %, 17.8 % on the HRCT, respectively. The OR of the emphysema prevalence in MEG was 2.92 (95 % CI 1.77-4.83) on the chest films, 2.56 (95 % CI 1.64-3.99) on the HRCT after sex, age, body mass index (BMI), smoking history, residency period and firewood used history were adjusted. The OR in the less than 29 pack-years smoking history was 1.66 (95 % CI 0.92-3.06) and in the more than 30 pack-years was 3.05 (95 % CI 1.68-5.52) on the chest films, and was 1.68 (95 % CI 0.98-2.90), 2.93 (95 % CI 1.72-4.98) on the HRCT, respectively.
The emphysema prevalence seems to be affected by the level of exposure to air pollution derived from the cement plant as well as sex, age, BMI, and smoking history in this study. Moreover, the OR of the case of the more exposed to the air pollution was similar to that of the case in smoking.
确定韩国一家水泥厂排放的空气污染对肺部健康的不良影响。通过胸部X光片（正位和侧位）及高分辨率计算机断层扫描（HRCT）肺部图像，比较水泥厂周边居民与居住在远离该厂地区居民的肺气肿患病率。
2013年6月至8月以及2014年8月至11月，对居住在一家水泥厂周边40岁以上居民进行胸部X光片及HRCT扫描。居民被分为两组；“高暴露组（MEG）”，由居住在半径1公里范围内的1046人组成，以及“低暴露组（LEG）”，由居住在距离同一家工厂5公里以外的317人组成。我们通过对胸部X光片和HRCT使用卡方检验及逻辑回归，比较了肺气肿患病率并估算了MEG和LEG之间的比值比（OR）。
LEG的肺气肿患病率在胸部X光片上为9.1%，MEG为14.3%；在HRCT上分别为11.4%、17.8%。在对性别、年龄、体重指数（BMI）、吸烟史、居住时间及使用柴火史进行调整后，MEG肺气肿患病率在胸部X光片上的OR为2.92（95%置信区间1.77 - 4.83），在HRCT上为2.56（95%置信区间1.64 - 3.99）。胸部X光片上，吸烟史小于29包年的OR为1.66（95%置信区间0.92 - 3.06），大于30包年的为3.05（95%置信区间1.68 - 5.52）；HRCT上分别为1.68（95%置信区间0.98 - 2.90）、2.93（95%置信区间1.72 - 4.98）。
在本研究中，肺气肿患病率似乎受水泥厂排放的空气污染暴露水平影响，同时也受性别、年龄、BMI及吸烟史影响。此外，空气污染高暴露组的OR与吸烟组相似。
