Wan Jie-Ping, Gao Yong
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P. R. China.
Chem Rec. 2016 Jun;16(3):1164-77. doi: 10.1002/tcr.201500296. Epub 2016 Apr 5.
Electron-deficient enamines such as enaminones and enaminoesters are moieties showing widespread application in organic synthesis. Among the various available electron-deficient enamines, the N,N-disubstituted amino-functionalized ones (tertiary enamines) represent a class of special enamines with distinct properties and important applications. Based on our longstanding interest in exploring novel synthetic methods using electron-deficient tertiary enamines, we present herein the research advances in organic synthesis via domino reactions making use of the combinatorial C-N, C=C, C-H, and other bond transformations of electron-deficient tertiary enamines.
缺电子烯胺，如烯胺酮和烯胺酯，是在有机合成中具有广泛应用的部分。在各种可用的缺电子烯胺中，N,N-二取代氨基官能化的烯胺（叔烯胺）代表了一类具有独特性质和重要应用的特殊烯胺。基于我们长期以来对探索使用缺电子叔烯胺的新型合成方法的兴趣，我们在此展示了通过多米诺反应利用缺电子叔烯胺的组合C-N、C=C、C-H和其他键转化进行有机合成的研究进展。
