Chawla Rohan, Venkatesh Pradeep
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India.
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India.
Med Hypotheses. 2016 May;90:48-50. doi: 10.1016/j.mehy.2016.03.001. Epub 2016 Mar 10.
In-vitro immunofluorescent assays/imaging are routinely used methods of detecting antigens. The ability to perform ocular angiography to study the choroidal and retinal vasculature in real time provides us with a unique opportunity to perform real time in-vivo immunofluorescent imaging. This unique combination of in-vivo immunofluorescent imaging and live imaging of choroidal and retinal circulation can help detect antigens of infective organisms in-vivo to diagnose causative infective aetiology in cases of choroiditis/retinitis. The following paper describes the basic designing of such an imaging platform.
体外免疫荧光测定/成像为检测抗原的常用方法。实时进行眼部血管造影以研究脉络膜和视网膜脉管系统的能力,为我们提供了进行实时体内免疫荧光成像的独特机会。体内免疫荧光成像与脉络膜和视网膜循环的实时成像的这种独特结合,有助于在体内检测感染性生物体的抗原,以诊断脉络膜炎/视网膜炎病例中的致病感染病因。以下论文描述了这种成像平台的基本设计。