Ogbonna Onyekachi Henry, Sakruti Susmita, Sulieman Maha, Ali Ahmed, Shokrani Babak, Oneal Patricia
Division of Hematology and Oncology, Department of Internal Medicine, Howard University Hospital, Washington, D.C., USA.
Departments of Internal Medicine, Howard University Hospital, Washington, D.C., USA.
Case Rep Oncol. 2016 Mar 12;9(1):182-7. doi: 10.1159/000444746. eCollection 2016 Jan-Apr.
Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor distinguished by having both hepatoid and adenomatous features, which can make the diagnosis challenging. Although it mostly originates in the stomach, several other sites of origin have been reported. We report a case of HAC originating in the duodenum, a very unusual location. We also discuss an approach to the diagnosis of HAC using morphological and immunohistochemical features, and explore possible therapeutic options.
肝样腺癌(HAC)是一种罕见的肝外肿瘤,其特征是具有肝样和腺瘤样特征,这可能使诊断具有挑战性。虽然它大多起源于胃,但也有报道称其起源于其他几个部位。我们报告一例起源于十二指肠的HAC病例,这是一个非常不寻常的部位。我们还讨论了一种利用形态学和免疫组化特征诊断HAC的方法,并探讨了可能的治疗选择。