胆囊肝样腺癌——一种罕见变体
Hepatoid Adenocarcinoma of the Gall Bladder-A Rare Variant.
作者信息
Devi Nalli R Sumitra, Sathyalakshmi R, Devi J, Lilly S Mary
机构信息
Professor, Department of Pathology, Stanley Medical College , Tamil Nadu Dr. MGR Medical University, India .
Assistant Professor, Department of Pathology, Stanley Medical College , Tamil Nadu Dr. MGR Medical University, India .
出版信息
J Clin Diagn Res. 2015 Aug;9(8):ED09-10. doi: 10.7860/JCDR/2015/10799.6324. Epub 2015 Aug 1.
Abstract
Hepatoid adenocarcinoma is a rare variant of extra hepatic adenocarcinoma, consisting of foci of both adenomatous and hepatocellular differentiation with morphological and functional resemblance to hepatocellular carcinoma and hence correct diagnosis is a challenge. The most frequent site is stomach. We present this case of hepatoid carcinoma of the gallbladder for its rarity and difficulty in diagnosis which on histology showed papillae, sheets and trabaculae of polygonal cells with eosinophilic cytoplasm and vesicular nuclei with prominent nucleoli with adjacent foci showing high grade dysplasia.
摘要
肝样腺癌是肝外腺癌的一种罕见变体，由腺瘤样和肝细胞样分化灶组成，在形态和功能上与肝细胞癌相似，因此正确诊断具有挑战性。最常见的部位是胃。我们报告这例胆囊肝样癌，因其罕见且诊断困难，组织学显示为多边形细胞的乳头、片状和小梁结构，细胞质嗜酸性，核呈泡状，核仁突出，相邻病灶显示高级别发育异常。
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